Condensed Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Operating activities
Net loss	$ (123,055)	$ (134,603)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation expense	303	306
Amortization of premiums and discounts on investments	372	0
Amortization of debt issuance costs	800	804
Non-cash interest expense related to the revenue interest liability	22,228	12,865
Stock-based compensation expense	7,963	14,335
Changes in assets and liabilities:
Accounts receivable	(4,910)	(9,466)
Prepaids and other assets	2,754	1,990
Deferred revenue	(1,078)	3,325
Inventories	5,162	(7,578)
Accounts payable	(4,640)	(22,182)
Other accrued liabilities	4,579	3,270
Net cash used in operating activities	(89,522)	(136,934)
Investing activities
Purchases of investments	(18,102)	0
Proceeds from sales/maturities of investments	5,000	0
Net cash used in investing activities	(13,102)	0
Financing activities
Proceeds from revenue interest liability, net of issuance costs	0	49,917
Proceeds from exercise of common stock options	0	2,836
Proceeds from issuance of common stock, net of issuance costs	20,209	0
Payments on revenue interest liability	(3,318)	(1,155)
Payment of issuance costs	(219)	(440)
Net cash provided by financing activities	16,672	51,158
Net decrease in cash and cash equivalents	(85,952)	(85,776)
Cash, cash equivalents and restricted cash at beginning of period	258,892	304,962
Cash, cash equivalents and restricted cash at end of period	172,940	219,186
Supplemental disclosure of cash flow information:
Issuance costs not yet paid	36	0
Non cash right of use asset	$ 12	$ 6