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Stock Compensation - Schedule of Stock Options (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Number of Options    
Outstanding at the beginning of period (in shares) 3,214,537  
Granted (in shares) 1,042,450  
Forfeited or expired (in shares) (155,728)  
Exercised (in shares) 0  
Outstanding at the end of the period (in shares) 4,101,259 3,214,537
Vested and expected to vest (in shares) 4,101,259  
Exercisable (in shares) 2,491,684  
Weighted-Average Exercise Price Per Share    
Outstanding at the beginning of period (in dollars per share) $ 38.38  
Granted (in dollars per share) 4.64  
Forfeited or expired (in dollars per share) 47.81  
Exercised (in dollars per share) 0  
Outstanding at the end of the period (in dollars per share) 29.44 $ 38.38
Vested and expected to vest (in dollars per share) 29.44  
Exercisable (in dollars per share) $ 39.84  
Weighted-Average Remaining Contractual Term (Years)    
Outstanding 5 years 7 months 13 days 4 years 2 months 4 days
Vested and expected to vest 5 years 7 months 13 days  
Exercisable 3 years 1 month 2 days  
Aggregate Intrinsic Value    
Outstanding $ 99 $ 0
Vested and expected to vest 99  
Exercisable $ 0