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Convertible Notes (Details)
3 Months Ended
Nov. 03, 2021
shares
Oct. 22, 2021
USD ($)
$ / shares
Jan. 01, 2021
USD ($)
Nov. 16, 2020
USD ($)
day
$ / shares
shares
Mar. 31, 2022
USD ($)
$ / shares
shares
Mar. 31, 2021
USD ($)
Dec. 31, 2021
USD ($)
$ / shares
Dec. 02, 2021
$ / shares
Nov. 18, 2020
USD ($)
Debt Instrument [Line Items]                  
Purchase of capped call options associated with convertible notes       $ 46,000,000          
Prepayment of forward stock repurchase transaction       $ 55,000,000          
Common stock, par value (in dollars per share) | $ / shares         $ 0.001   $ 0.001    
Additional Paid in Capital         $ (969,268,000)   $ (964,401,000)    
Accumulated Deficit         $ 1,163,108,000   $ 1,106,377,000    
Exercise price (in dollars per share) | $ / shares         $ 9.00   $ 9.00 $ 9.00  
Underlying common stock (in shares) | shares       1,994,198          
Shares delivered to the company (in shares) | shares         71,174        
Cumulative Effect, Period of Adoption, Adjustment                  
Debt Instrument [Line Items]                  
Additional Paid in Capital     $ 93,500,000            
Accumulated Deficit     1,500,000            
Capped Call | Common stock                  
Debt Instrument [Line Items]                  
Exercise price (in dollars per share) | $ / shares       $ 55.16          
Class of warrant or right, premium percentage       100.00%          
Convertible Senior Notes Due 2025 | Convertible Debt                  
Debt Instrument [Line Items]                  
Debt instrument, face amount       $ 280,000,000         $ 280,000,000
Debt instrument, stated interest rate       4.00%          
Proceeds from debt, net of issuance costs     $ 271,100,000 $ 271,100,000          
Debt instrument, convertible, conversion ratio       30.2151          
Debt instrument, convertible, conversion price (in dollars per share) | $ / shares       $ 33.096          
Debt instrument, redemption price, percentage       100.00%          
Debt issuance costs       $ 8,900,000          
Debt instrument, term       5 years          
Long-term debt       $ 177,600,000 $ 258,700,000        
Debt instrument, convertible, carrying amount of equity component       $ 93,500,000          
Exchange Agreement, amount of principal amount converted into common stock   $ 15,000,000              
Exchange Agreement, weighted average price per share floor (in dollars per share) | $ / shares   $ 5.62              
Exchange Agreement, threshold trading days   5 days              
Common stock being exchanged (in shares) | shares 1,094,848                
Principal amount of convertible notes         265,000,000        
Unamortized debt discount and issuance costs         6,300,000        
Debt interest expense         3,000,000 $ 3,200,000      
Debt fair value         $ 137,100,000   $ 140,300,000    
Convertible Senior Notes Due 2025 | Convertible Debt | Period One                  
Debt Instrument [Line Items]                  
Common stock, par value (in dollars per share) | $ / shares       $ 0.001          
Debt instrument, convertible, threshold percentage of stock price trigger       130.00%          
Debt instrument, convertible, threshold trading days | day       20          
Average trading-day period | day       30          
Number of business days | day       5          
Number of consecutive trading days | day       5          
Debt instrument, convertible, threshold percentage of last reported sale price       98.00%          
Convertible Senior Notes Due 2025 | Convertible Debt | Period Two                  
Debt Instrument [Line Items]                  
Debt instrument, convertible, threshold percentage of stock price trigger       130.00%          
Debt instrument, convertible, threshold trading days | day       20          
Average trading-day period | day       30          
Debt instrument, redemption price, percentage       100.00%          
Debt instrument, required amount outstanding       $ 125,000,000          
Convertible Senior Notes Due 2025 | Convertible Debt | Long-term Debt                  
Debt Instrument [Line Items]                  
Debt issuance costs       5,800,000          
Convertible Senior Notes Due 2025 | Convertible Debt | Additional Paid-In Capital                  
Debt Instrument [Line Items]                  
Debt issuance costs       $ 3,100,000