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Net Loss Per Common Share
 12 Months Ended
Dec. 31, 2021
Earnings Per Share [Abstract]  
Net Loss Per Common Share Net Loss Per Common Share
Basic net loss per share is calculated by dividing net loss by the weighted-average number of common shares outstanding during the period, without consideration for common stock equivalents. Diluted net loss per share is computed by dividing net loss by the weighted-average number of common stock equivalents outstanding for the period determined using the treasury-stock method. For purposes of this calculation, warrants for common stock, stock options, PBSOs, unvested RSUs and PBRSUs, shares issuable under the ESPP and shares issuable upon conversion of the convertible notes are considered to be common stock equivalents and are only included in the calculation of diluted net loss per share when their effect is dilutive.
The shares outstanding at the end of the respective periods presented below were excluded from the calculation of diluted net loss per share due to their anti-dilutive effect:
December 31,
2021		December 31,
2020		December 31,
2019
Common shares under option3,214,537 4,176,518 4,677,929 
Unvested RSUs698,704 401,234 245,966 
Shares issuable related to the ESPP23,448 16,828 — 
Unvested PBRSUs639,950 — — 
Common shares under PBSOs122,700 — — 
Shares issuable upon conversion of convertible notes8,007,010 8,460,237 — 
Warrants for common stock36,964,286 — — 
Total potential dilutive shares49,670,635 13,054,817 4,923,895