Condensed Statements of Operations and Comprehensive (Loss) Income - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Revenues:
Total Revenues	$ 14,409	$ 3,833	$ 63,046	$ 217,909
Operating expenses:
Cost of goods sold	5,558	275	9,142	704
Research and development	25,331	35,283	78,359	104,972
Selling, general and administrative	39,265	48,826	146,647	138,060
Total operating expenses	70,154	84,384	234,148	243,736
Loss from operations	(55,745)	(80,551)	(171,102)	(25,827)
Interest expense	(13,654)	(4,928)	(32,923)	(13,739)
Other income, net	13	42	36	491
Net loss	$ (69,386)	$ (85,437)	$ (203,989)	$ (39,075)
Net loss per common share - basic (in dollars per share)	$ (2.62)	$ (3.07)	$ (7.78)	$ (1.41)
Net loss per common share - diluted (in dollars per share)	$ (2.62)	$ (3.07)	$ (7.78)	$ (1.41)
Weighted-average shares outstanding - basic (in shares)	26,455,209	27,830,281	26,225,730	27,672,325
Weighted-average shares outstanding - diluted (in shares)	26,455,209	27,830,281	26,225,730	27,672,325
Other comprehensive loss:
Unrealized loss on investments	$ 0	$ 0	$ 0	$ (23)
Comprehensive loss	(69,386)	(85,437)	(203,989)	(39,098)
Product sales, net
Revenues:
Total Revenues	10,895	3,331	27,855	4,798
Collaboration revenue
Revenues:
Total Revenues	$ 3,514	$ 502	$ 35,191	$ 213,111