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The Company and Basis of Presentation (Details)
$ in Thousands
1 Months Ended
Oct. 18, 2021
employee
Apr. 26, 2021
USD ($)
May 31, 2021
USD ($)
Sep. 30, 2021
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Dec. 31, 2019
USD ($)
The Company and Basis of Presentation              
Restricted cash       $ 50,000 $ 0 $ 0 $ 928
Subsequent Event              
The Company and Basis of Presentation              
Reduction in workforce (percentage) 40.00%            
Reduction in workforce employees | employee 170            
Daiichi Sankyo Co. Ltd | License and Collaboration Agreement              
The Company and Basis of Presentation              
Upfront cash payment received (paid)     $ 30,000        
Potential additional future payments   $ 175,000          
Daiichi Sankyo Co. Ltd | License and Collaboration Agreement | Minimum              
The Company and Basis of Presentation              
Percentage of royalties to be received on the net sales   5.00%          
Daiichi Sankyo Co. Ltd | License and Collaboration Agreement | Maximum              
The Company and Basis of Presentation              
Percentage of royalties to be received on the net sales   20.00%          
Oberland | RIPA Amendment              
The Company and Basis of Presentation              
Proceeds from Revenue Interest Purchase Agreement   $ 50,000