X0306 4 2018-02-22 0 0001434868 Esperion Therapeutics, Inc. ESPR 0001596932 Berkowitz Jeffrey C/O ESPERION THERAPEUTICS, INC. ANN ARBOR MI 48108 1 0 0 0 Stock option (right to buy) 77.94 2018-02-22 4 A 0 25000 0.00 A 2028-02-22 Common Stock 25000 25000 D Vests in equal monthly installments rounded down to the nearest whole share over the 36 months following December 14, 2017, with the balance of the options vesting on the last monthly vesting date which is the third anniversary of December 14, 2017. /s/ Richard B. Bartram, by power of attorney 2018-02-23