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Commitments and contingencies (Details) (USD $)
1 Months Ended 6 Months Ended 1 Months Ended
Feb. 28, 2014
Jun. 30, 2014
May 31, 2014
Third amendment to the operating lease agreement for laboratory facility in Plymouth, Michigan
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Commitments and contingencies      
Term period of lease 63 months    
Operating lease period for monthly rent increasing in fixed monthly rent   12 months  
Operating lease period after which monthly rent increase   3 months  
Commitments and contingencies      
Adjusted rentable laboratory space (in square feet)     3,045
Adjusted proportionate share of landlord's expenses and taxes (as a percent)     7.40%
Number of terms which Company may exercise to renew lease     1
Lease renewal term     3 years
Annual base rent under new lease agreement     $ 37,000
Operating leases      
Total   615,000  
Less than 1 Year   128,000  
1-3 Years   267,000  
3-5 Years   211,000  
More than 5 Years   9,000  
Total      
Total   615,000  
Less than 1 Year   128,000  
1-3 Years   267,000  
3-5 Years   211,000  
More than 5 Years   $ 9,000