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Condensed Balance Sheets (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2014
Dec. 31, 2013
Current assets:    
Cash and cash equivalents $ 85,038us-gaap_CashAndCashEquivalentsAtCarryingValue $ 56,537us-gaap_CashAndCashEquivalentsAtCarryingValue
Short-term investments 20,803us-gaap_ShortTermInvestments 3,525us-gaap_ShortTermInvestments
Prepaid clinical development costs 366espr_PrepaidClinicalDevelopmentCostsCurrent 196espr_PrepaidClinicalDevelopmentCostsCurrent
Other prepaid and current assets 560espr_OtherPrepaidExpenseAndAssetsCurrent 362espr_OtherPrepaidExpenseAndAssetsCurrent
Total current assets 106,767us-gaap_AssetsCurrent 60,620us-gaap_AssetsCurrent
Property and equipment, net 780us-gaap_PropertyPlantAndEquipmentNet 81us-gaap_PropertyPlantAndEquipmentNet
Intangible assets 56us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill 56us-gaap_IndefiniteLivedIntangibleAssetsExcludingGoodwill
Long-term investments 35,741us-gaap_LongTermInvestments 17,537us-gaap_LongTermInvestments
Total assets 143,344us-gaap_Assets 78,294us-gaap_Assets
Current liabilities:    
Accounts payable 2,040us-gaap_AccountsPayableCurrent 2,232us-gaap_AccountsPayableCurrent
Current portion of long-term debt 638us-gaap_LongTermDebtCurrent  
Accrued clinical development costs 1,978espr_AccruedClinicalDevelopmentCostsCurrent 884espr_AccruedClinicalDevelopmentCostsCurrent
Other accrued liabilities 835us-gaap_OtherAccruedLiabilitiesCurrent 1,087us-gaap_OtherAccruedLiabilitiesCurrent
Total current liabilities 5,491us-gaap_LiabilitiesCurrent 4,203us-gaap_LiabilitiesCurrent
Long-term debt, net of discount 4,299us-gaap_LongTermDebtNoncurrent  
Total liabilities 9,790us-gaap_Liabilities 4,203us-gaap_Liabilities
Commitments and contingencies (Note 5)      
Stockholders' equity:    
Preferred stock, $0.001 par value; 5,000,000 shares authorized and no shares issued or outstanding as of December 31, 2014 and December 31, 2013      
Common stock, $0.001 par value; 120,000,000 shares authorized as of December 31, 2014 and December 31,2013; 20,352,876 shares issued 20,343,325 outstanding at December 31, 2014 and 15,357,413 shares issued and 15,340,710 outstanding at December 31, 2013 20us-gaap_CommonStockValue 15us-gaap_CommonStockValue
Additional paid-in capital 238,031us-gaap_AdditionalPaidInCapital 142,142us-gaap_AdditionalPaidInCapital
Accumulated other comprehensive loss (59)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax (3)us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax
Accumulated deficit (104,438)us-gaap_RetainedEarningsAccumulatedDeficit (68,063)us-gaap_RetainedEarningsAccumulatedDeficit
Total stockholders' equity 133,554us-gaap_StockholdersEquity 74,091us-gaap_StockholdersEquity
Total liabilities and stockholders' equity $ 143,344us-gaap_LiabilitiesAndStockholdersEquity $ 78,294us-gaap_LiabilitiesAndStockholdersEquity