Note H - Fair Value of Financial Instruments (Details Textual)	3 Months Ended
	Mar. 31, 2022 USD ($)	Dec. 31, 2021 USD ($)
Deerfield Warrant Liability [Member]
Liabilities, Fair Value Disclosure, Total	$ 80,000	$ 288,000
Liabilities, Fair Value Disclosure, Increase from Ten Percent Increase in Enterprise Value	16,000
Liabilities, Fair Value Disclosure, Estimated Amount of Weighted-average Probability of Liquidity Event	30,000,000.0
Liabilities, Fair Value Disclosure, Estimated Amount of Weighted-average Probability of Fundamental Change	$ 390,000,000
Deerfield Warrant Liability [Member] | Weighted Average Probability of Liquidity Event [Member]
Derivative Liability, Measurement Input	0.23
Deerfield Warrant Liability [Member] | Weighted Average Probability of Fundamental Change [Member]
Derivative Liability, Measurement Input	33
Embedded Put Option [Member]
Liabilities, Fair Value Disclosure, Total	$ 4,000	$ 18,000
Liabilities, Fair Value Disclosure, Increase from Ten Percent Increase in Enterprise Value	$ 1,000