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Note H - Fair Value of Financial Instruments (Tables)
3 Months Ended
Mar. 31, 2022
Notes Tables  
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
  Balance as of March 31, 2022  Quoted Prices in Active Markets for Identical Assets (Level 1)  Significant Other Observable Inputs (Level 2)  Significant Unobservable Inputs (Level 3) 

Deerfield Warrant liability

 $80  $  $  $80 

Embedded Warrant Put Option

  4         4 

KVK Warrant liability

  5      5    

Total liabilities

 $89  $  $5  $84 
                 

Trading securities:

                

U.S. government-sponsored agency securities

 $7,335  $  $7,335  $ 

Corporate notes and commercial paper

  1,338      1,338    

Certificates of deposit

  481   481       

U.S. Treasury securities

  9,748   9,748       

Total assets

 $18,902  $10,229  $8,673  $ 
  Balance as of December 31, 2021  Quoted Prices in Active Markets for Identical Assets (Level 1)  Significant Other Observable Inputs (Level 2)  Significant Unobservable Inputs (Level 3) 

Deerfield Warrant liability

 $288  $  $  $288 

Embedded Warrant Put Option

  18         18 

KVK Warrant liability

  24      24    

Total liabilities

 $330  $  $24  $306 
                 

Trading securities:

                

U.S. government-sponsored agency securities

 $4,997  $  $4,997  $ 

Certificates of deposit

  490   490       

U.S. Treasury securities

  9,935   9,935       

Total assets

 $15,422  $10,425  $4,997  $ 
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
  

Three months ended March 31,

 
  

2022

  

2021

 

Balance as of beginning of period

 $306  $255 

Adjustment to fair value

  (222)  37 

Balance as of end of period

 $84  $292