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Note O - Net Loss Per Share (Tables)
12 Months Ended
Dec. 31, 2019
Notes Tables  
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
   
Year Ended December 31,
   
2019
 
2018
Net loss - basic and diluted
  $
(24,522
)
  $
(56,466
)
Weighted average number of shares of common stock - basic and diluted
   
29,654,968
 
   
17,930,023
 
Net loss per share - basic and diluted
  $
(0.83
)
  $
(3.15
)
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
   
December 31,
   
2019
 
2018
Deerfield Convertible Note
   
1,213,606
 
   
1,167,607
 
2021 Notes
   
175,336
 
   
4,481,182
 
2019 Notes*    
29,625,785
 
   
-
 
Awards under equity incentive plans
   
5,192,222
 
   
3,704,755
 
Common stock warrants
   
2,423,077
 
   
2,527,763
 
Series A Convertible Preferred Stock
   
-
 
   
1,112,334
 
Total securities excluded from the calculation of weighted average number of shares of common stock outstanding
   
38,630,026
 
   
12,993,641