Note C - Debt Obligations (Details Textual) - USD ($)					3 Months Ended
	Oct. 05, 2018	Jun. 11, 2018	Feb. 09, 2016	Jun. 02, 2014	Mar. 31, 2019	Mar. 31, 2018	Nov. 20, 2018	Jun. 30, 2016
Interest Paid, Excluding Capitalized Interest, Operating Activities					$ 2,287,000	$ 2,618,000
Conversion from Deerfield Convertible Note to Common Stock [Member]
Debt Conversion, Converted Instrument, Shares Issued		598,568
Debt Conversion, Original Debt, Amount		$ 3,333,333
Debt Conversion, Accrued Interest		$ 168,288
Exchanged 2021 Notes for Series A Preferred Stock [Member]
Debt Conversion, Converted Instrument, Shares Issued	9,577
Debt Conversion, Original Debt, Amount	$ 9,577,000
Interest Paid, Excluding Capitalized Interest, Operating Activities	95,105
Debt Conversion, Expenses, Reimbursement	$ 25,000
Preferred Stock, Aggregate Stated Value Per Share	$ 1,000
Convertible Notes 2021 [Member]
Beneficial Ownership, Cap Limit, Percentage							9.985%
Deerfield Convertible Notes [Member]
Beneficial Ownership, Cap Limit, Percentage							4.985%
Series A Preferred Stock [Member]
Preferred Stock, Par or Stated Value Per Share	0.0001		$ 0.0001
Preferred Stock, Aggregate Stated Value Per Share	1,000
Convertible Preferred Stock, Conversion Price	$ 3
Convertible Preferred Stock, Shares Issuable Upon Conversion	3,192,334				1,112,334
Convertible Preferred Stock, Conversion Restriction, Percentage of Common Stock	4.985%
2021 Notes [Member]
Debt Instrument, Convertible, Conversion Price			$ 17.11
Debt Instrument, Face Amount			$ 86,300,000
Debt Instrument, Interest Rate, Stated Percentage			5.50%
Proceeds from Debt, Net of Issuance Costs			$ 82,800,000
Repayments of Long-term Debt, Total			18,600,000
Debt Instrument, Sinking Fund Payment			$ 0
Debt Conversion, Converted Instrument, Shares Issued			58.4454
Debt Conversion, Original Debt, Amount			$ 1,000
Debt Instrument Repurchase Price Equal to Percentage of Principal Amount			100.00%
Deerfield Facility Agreement [Member]
Line of Credit Facility, Maximum Borrowing Capacity				$ 60,000,000
Line of Credit Facility, Interest Rate at Period End				9.75%
Debt Covenant, Debt Financing Restriction				$ 750,000
Deerfield Facility Agreement [Member] | Deerfield Warrant [Member]
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 0.78
Deerfield Facility Agreement [Member] | Deerfield Warrant [Member] | IPO [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights				1,923,077
Deerfield Facility Agreement [Member] | Series D Redeemable Convertible Preferred Stock [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights				14,423,076
Own-share Lending Arrangement, Shares, Issued				1,923,077
Mandatorily Redeemable Preferred Stock, Fair Value Disclosure				$ 1,500,000
Deerfield Facility Agreement [Member] | Initial Public Offering [Member]
Reclassification of Common Stock Shares				256,410
Deerfield Facility Agreement [Member] | Term Notes [Member]
Proceeds from Secured Notes Payable				$ 15,000,000
Deerfield Facility Agreement [Member] | Deerfield Convertible Notes [Member]
Proceeds from Secured Notes Payable				$ 10,000,000
Debt Instrument, Convertible, Conversion Price				$ 5.85
Third Line of Credit Agreement [Member] | City National Bank of Florida [Member]
Line of Credit Facility, Maximum Borrowing Capacity								$ 1,100,000