X0202 SCHEDULE 13G/A 0000902664-24-006572 0001784547 XXXXXXXX LIVE 2 Common Stock, par value $0.0001 per share 06/30/2026 0001434647 Zevra Therapeutics, Inc. 488445206 101 FEDERAL STREET BOSTON MA 02110 Rule 13d-1(b) Woodline Partners LP DE 4785771.00 0.00 4785771.00 0.00 4785771.00 N 8.1 IA PN Zevra Therapeutics, Inc. 101 Federal Street, Boston, MA 02110 This statement is filed by Woodline Partners LP ("Woodline Partners" or the "Reporting Person"), a Delaware limited partnership, and the investment adviser to Woodline Master Fund LP and Woodline Spire Master Fund LP (together, the "Woodline Funds"), with respect to the shares of common stock, par value $0.0001 per share ("Common Stock"), of Zevra Therapeutics, Inc. (the "Company") directly held by the Woodline Funds. The filing of this statement should not be construed as an admission that any of the foregoing persons or the Reporting Person is, for the purposes of Section 13 of the Securities Exchange Act of 1934, the beneficial owner of the shares of Common Stock reported herein. The address of the business office of Woodline Partners is 4 Embarcadero Center, Suite 3450, San Francisco, CA 94111. Woodline Partners is a Delaware limited partnership. N IA The information required by Item 4(a) is set forth in Row 9 of the cover page for the Reporting Person and is incorporated herein by reference. The percentage set forth in this Schedule 13G is calculated based upon an aggregate of 59,115,084 shares of Common Stock outstanding as of May 1, 2026, as reported in the Company's Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2026, filed with the Securities and Exchange Commission on May 6, 2026. 8.1% The information required by Item 4(c)(i) is set forth in Row 5 of the cover page for the Reporting Person and is incorporated herein by reference. The information required by Item 4(c)(ii) is set forth in Row 6 of the cover page for the Reporting Person and is incorporated herein by reference. The information required by Item 4(c)(iii) is set forth in Row 7 of the cover page for the Reporting Person and is incorporated herein by reference. The information required by Item 4(c)(iv) is set forth in Row 8 of the cover page for the Reporting Person and is incorporated herein by reference. Y N See Item 2(a). Woodline Master Fund LP has right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the shares of Common Stock reported herein. Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11. Woodline Partners LP /s/ Erin Mullen 08/14/2026