X0306 4 2021-07-22 0 0001434316 FATE THERAPEUTICS INC FATE 0001586893 Wolchko J Scott FATE THERAPEUTICS, INC. 3535 GENERAL ATOMICS COURT, SUITE 200 SAN DIEGO CA 92121 1 1 0 0 President and CEO Common Stock 2021-07-22 4 M 0 30000 2.73 A 423793 D Common Stock 2021-07-22 4 S 0 6627 85.3811 D 417166 D Common Stock 2021-07-22 4 S 0 21773 86.1944 D 395393 D Common Stock 2021-07-22 4 S 0 1600 86.9026 D 393793 D Common Stock 2021-07-23 4 M 0 10000 2.73 A 403793 D Common Stock 2021-07-23 4 M 0 20000 4.84 A 423793 D Common Stock 2021-07-23 4 S 0 30000 85.2846 D 393793 D Stock Option (Right to Buy) 2.73 2021-07-22 4 M 0 30000 0.00 D 2027-01-03 Common Stock 30000 100000 D Stock Option (Right to Buy) 2.73 2021-07-23 4 M 0 10000 0.00 D 2027-01-03 Common Stock 10000 90000 D Stock Option (Right to Buy) 4.835 2021-07-23 4 M 0 20000 0.00 D 2025-01-04 Common Stock 20000 24846 D This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 10, 2020. Represents the weighted average sale price of the shares sold ranging from $84.76 to $85.74 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price. Represents the weighted average sale price of the shares sold ranging from $85.76 to $86.75 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price. Represents the weighted average sale price of the shares sold ranging from $86.76 to $87.15 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each price. This option is fully vested. /s/ Cindy Tahl, Attorney-in-Fact 2021-07-26