X0306 4 2021-06-02 0 0001434316 FATE THERAPEUTICS INC FATE 0001205903 RASTETTER WILLIAM H FATE THERAPEUTICS, INC. 3535 GENERAL ATOMICS COURT, SUITE 200 SAN DIEGO CA 92121 1 0 0 0 Common Stock 2021-06-02 4 A 0 2681 0.00 A 2681 D Common Stock 146821 I By The Rastetter Family Trust, dated 09/02/10 Common Stock 459272 I By The Investment 2002 Trust dated 11/11/02 Stock Option (Right to Buy) 68.94 2021-06-02 4 A 0 4334 0.00 A 2031-06-01 Common Stock 4334 4334 D Award of restricted stock units that vest in full on the earlier of (i) June 2, 2022 or (ii) the date of the Issuer's 2022 Annual Meeting of Stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors. These shares are owned of record by The Investment 2002 Trust, dated November 11, 2002 for which William H. Rastetter is the sole trustee and owner. These shares are owned of record by The Rastetter Family Trust, dated September 2, 2010 for which William H. Rastetter and Marisa Gard Rastetter serve as co-trustee The shares subject to this option shall vest and become exercisable on the earlier of (i) June 2, 2022 or (ii) the date of the Issuer's 2022 Annual Meeting of Stockholders, subject to the Reporting Person's continued service on the Issuer's Board of Directors. /s/ Cindy R. Tahl, as Attorney-in-Fact 2021-06-04