EQUITY (Details Narrative) - USD ($)	3 Months Ended
Mar. 31, 2022	Dec. 31, 2021
Class of Stock [Line Items]
Common stock, shares outstanding	8,317,876	8,296,256
Capital stock shares authorized	155,000,000
Capital stock par value	$ 0.0001
Common stock shares authorized	150,000,000	150,000,000
Stock option description	7,841 options are subject to a three-year vesting period, with one-third of such awards vesting each year and 40,000 options with performance conditions, mainly related to clinical activities.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate	0.00%
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum	127.92%
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum	130.93%
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum	1.79%
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum	1.90%
Three Year Vesting Period [Member]
Class of Stock [Line Items]
Employees stock option grant	7,841,000
Performance Conditions [Member]
Class of Stock [Line Items]
Employees stock option grant	40,000
Minimum [Member]
Class of Stock [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term	5 years 6 months
Maximum [Member]
Class of Stock [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term	6 years 6 months
Share-Based Payment Arrangement, Option [Member]
Class of Stock [Line Items]
Employees stock option grant	47,841
Vesting period	3 years
Fair value stock option price	$ 104,124
Share-Based Payment Arrangement, Option [Member] \| Minimum [Member]
Class of Stock [Line Items]
Stock option exercise price	$ 2.61
Share-Based Payment Arrangement, Option [Member] \| Maximum [Member]
Class of Stock [Line Items]
Stock option exercise price	$ 2.69
Restricted Stock [Member]
Class of Stock [Line Items]
Stock granted	26,183
Stock vesting period	3 years
Fair value of restricted shares	$ 68,338
Preferred Stock Blank Check [Member]
Class of Stock [Line Items]
Preferred stock shares authorized	5,000,000
At The Market Offering [Member] \| Warrant [Member]
Class of Stock [Line Items]
Purchase of warrants	1,793,815
Series C Convertible Preferred Stock [Member]
Class of Stock [Line Items]
Common stock, shares outstanding	1,718
Conversion of series b convertible preferred stock to common shares, shares	2,280

Capital stock par value.

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Fair value of restricted shares.

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Fair value of stock options.

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Stock vesting period.

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Number of authorized capital units or capital shares. This element is relevant to issuers of face-amount certificates and registered investment companies.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Number of warrants or rights outstanding.

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Number of shares of common stock outstanding. Common stock represent the ownership interest in a corporation.

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The maximum number of nonredeemable preferred shares (or preferred stock redeemable solely at the option of the issuer) permitted to be issued by an entity's charter and bylaws.

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Period over which grantee's right to exercise award under share-based payment arrangement is no longer contingent on satisfaction of service or performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. Includes, but is not limited to, combination of market, performance or service condition.

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Description of terms of share-based payment arrangement. Includes, but is not limited to, type of award or grantee and reason for issuance.

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The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.

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The estimated measure of the maximum percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period.

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The maximum risk-free interest rate assumption that is used in valuing an option on its own shares.

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The minimum risk-free interest rate assumption that is used in valuing an option on its own shares.

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Net number of share options (or share units) granted during the period.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days.

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Number of shares issued during the period as a result of the conversion of convertible securities.

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