Consolidated Statements of Changes in Equity - USD ($) $ in Thousands		Common Stock [Member]		Preferred Stock [Member] Series B Convertible Preferred Stock [Member]	Preferred Stock [Member] Series C Convertible Preferred Stock [Member]		Additional Paid-in Capital [Member]	Retained Earnings [Member]	Total
Beginning balance, value at Dec. 31, 2019							$ 163,015	$ (157,632)	$ 5,383
Beginning balance, shares at Dec. 31, 2019		261,075		17,303	34,370
Net loss								(10,544)	(10,544)
Exercise of pre-funded warrants			[1]				18		18
Exercise of pre-funded warrants, shares		990,427
Settlement of restricted stock units in shares of common stock	[1]
Settlement of restricted stock units in shares of common stock, shares		11,000
Issuance of common shares, including at the market offering net of issuance costs			[1]				15,200		15,200
Issuance of common shares, including at the market offering net of issuance costs, shares		1,607,251
Exercise of Warrants F			[1]				1,418		1,418
Exercise of Warrants F, shares		191,107
Exercise of Unit Purchase Option			[1]				82		82
Exercise of Unit Purchase Option, shares		16,906
Conversion of Series C Convertible Preferred Stock to common shares			[1]			[1]				[1]
Conversion of series C convertible preferred stock to common stock, shares		24,812			(32,027)
Share-based compensation related to restricted stock, restricted stock units and stock options award, net of forfeitures			[1]				606		606
Share-based compensation related to restricted stock, restricted stock units and stock options award, net of forfeitures, shares		181,744
Ending balance, value at Dec. 31, 2020							180,339	(168,176)	12,163
Ending balance, shares at Dec. 31, 2020		3,284,322		17,303	2,343
Net loss								(14,918)	(14,918)
Issuance of common shares, including at the market offering net of issuance costs		$ 1					25,241		25,242
Issuance of common shares, including at the market offering net of issuance costs, shares		3,133,775
Exercise of Warrants F			[2]				8,120		8,120
Exercise of Warrants F, shares		1,093,536
Exercise of Warrants G			[2]				1,349		$ 1,349
Exercise of Warrants G, shares		131,876
Conversion of Series B Convertible Preferred Stock to common shares	[2]
Conversion of series B convertible preferred stock to common stock, shares		207,528		(17,303)
Conversion of Series C Convertible Preferred Stock to common shares	[2]
Conversion of series C convertible preferred stock to common stock, shares		831			(625)
Share-based compensation related to restricted stock, restricted stock units and stock options award, net of forfeitures							1,576		1,576
Share-based compensation related to restricted stock, restricted stock units and stock options award, net of forfeitures, shares		399,120
Round up of shares due to reverse stock split effectuated on April 26, 2021			[2]							[2]
Round up of shares due to reverse stock split effectuated on April 26, 2021, shares		45,268
Ending balance, value at Dec. 31, 2021		$ 1					$ 216,625	$ (183,094)	$ 33,532
Ending balance, shares at Dec. 31, 2021		8,296,256			1,718

[1] Represents an amount less than $1

[2] Represents an amount less than $1