EQUITY (Details Narrative) - USD ($)							12 Months Ended		15 Months Ended
	Apr. 19, 2021	Feb. 08, 2021	Feb. 03, 2021	Jun. 05, 2020	Mar. 14, 2017	Jul. 07, 2016	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2020	Dec. 14, 2020	Jul. 28, 2020	Jun. 02, 2020	Dec. 31, 2019
Subsidiary, Sale of Stock [Line Items]
Reverse stock split	one-for-fifteen reverse stock split of its common stock
Common stock, par value	$ 0.0001						$ 0.0001	$ 0.0001	$ 0.0001
Warrants exercise price											$ 7.43
Outstanding pre-funded warrants are exercisable into shares of common stock								0	0
Warrants to purchase common stock							1,793,983				18,277
Capital stock shares authorized							155,000,000
Capital stock par value							$ 0.0001
Common stock shares authorized							150,000,000	150,000,000	150,000,000
Minimum [Member]
Subsidiary, Sale of Stock [Line Items]
Warrants exercise price											$ 2,812.5
Maximum [Member]
Subsidiary, Sale of Stock [Line Items]
Warrants exercise price											$ 33.75
Share-based Payment Arrangement, Option [Member]
Subsidiary, Sale of Stock [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Net of Forfeitures							225,225	92,007
Fair value of stock options							$ 1,026,000	$ 509,000
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period							3 years
Share-based Payment Arrangement, Option [Member] | Minimum [Member]
Subsidiary, Sale of Stock [Line Items]
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price							$ 3.89	$ 4.95
Share-based Payment Arrangement, Option [Member] | Maximum [Member]
Subsidiary, Sale of Stock [Line Items]
Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price							$ 10.05	$ 16.50
Restricted Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Stock granted							419,943	185,461
Fair value of restricted shares							$ 1,781,981	$ 1,051,604
Stock vesting period							3 years
Weighted average of the remaining contractual life of vested and exercisable options							8 years 7 months 24 days
Aggregate intrinsic value of exercisable options							$ 400,000
Weighted average fair value of options granted							4.56
Restricted Stock Units (RSUs) [Member]
Subsidiary, Sale of Stock [Line Items]
Stock granted							146,567	90,511
Stock vesting period							3 years
Fair value of restricted stock units							$ 603,856	$ 658,981
Employee and Non-employee Stock Options [Member]
Subsidiary, Sale of Stock [Line Items]
Unvested stock-based compensation							$ 3,400,000
Unvested stock-based compensation weighted-average period for recognition							1 year 3 days
Series B Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Preferred stock convertible, shares							17,303
Converted preferred stock							207,528
Preferred stock outstanding							0	17,303	17,303
Preferred stock shares authorized							500,000	500,000	500,000
Series C Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Preferred stock outstanding							1,718	2,343	2,343
Preferred stock shares authorized							1,172,000	1,172,000	1,172,000
Common Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering							3,133,775	1,607,251
Shares outstanding							8,296,256	3,284,322	3,284,322				261,075
Preferred Stock Blank Check [Member]
Subsidiary, Sale of Stock [Line Items]
Preferred stock shares authorized							5,000,000
Securities Purchase Agreement [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering			89,445
Share price			$ 10.062
Proceeds from sale of stock			$ 900,000
Underwritten Public Offering [Member]
Subsidiary, Sale of Stock [Line Items]
Common stock, par value		$ 0.0001		$ 0.0001
Number of issuance of public offering		1,935,484		509,053
Share price		$ 9.30		$ 6.75
Proceeds from exercise of warrants				$ 10,700,000
Warrants exercise price				$ 0.015
Net proceeds from issuance of stock		$ 18,900,000
Underwritten Public Offering [Member] | Series B Convertible Preferred Stock and Series C Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Share price				$ 6.75
Underwritten Public Offering [Member] | Series B Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Additional shares of common stock												111,028
Shares outstanding												17,303
Underwritten Public Offering [Member] | Series C Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Additional shares of common stock												18,886
Shares outstanding												26,558
Underwritten Public Offering [Member] | Common Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering							1,225,412
Over allotment shares		290,322		222,220
Conversion of convertible securities								191,107
Proceeds from sale of stock							$ 9,469,000
Underwritten Public Offering [Member] | Series F Warrants [Member]
Subsidiary, Sale of Stock [Line Items]
Over allotment shares				222,220
Warrants exercise price				$ 7.425			$ 7.425
Conversion of convertible securities								191,107
Proceeds from exercise of warrants								$ 1,400,000
Underwritten Public Offering [Member] | Series G Warrants [Member]
Subsidiary, Sale of Stock [Line Items]
Over allotment shares		145,161
Share price		$ 10.23
Warrants exercise price							$ 10.23
Warrants and Rights Outstanding, Term		5 years
Underwritten Public Offering [Member] | Warrant [Member]
Subsidiary, Sale of Stock [Line Items]
Warrants exercise price		$ 10.23
Warrants and Rights Outstanding, Term		5 years
Warrants to purchase common stock		111,290
Underwritten Public Offering [Member] | Pre-Funded Units [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering				972,427
Share price				$ 6.735
Underwritten Public Offering [Member] | Pre-Funded Warrants [Member]
Subsidiary, Sale of Stock [Line Items]
Number of shares issued for exercise of warrants								972,427	18,000
At The Market Offering [Member] | Series B Convertible Preferred Stock and Series C Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Share price				$ 4.815
At The Market Offering [Member] | Series B Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering						442,424
Share price						$ 495.00
Additional shares of common stock										59,491
Shares outstanding										17,303
Preferred stock convertible, shares						207,528
Conversion price per share						$ 4.815
Dividend rate						15.00%
At The Market Offering [Member] | Series C Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering					1,069,822
Share price					$ 96
Additional shares of common stock										893
Shares outstanding										2,343
Preferred stock convertible, shares					3,114
Conversion price per share					$ 4.815
Converted preferred stock							2,284
Preferred stock outstanding							1,718
At The Market Offering [Member] | Series C Convertible Preferred Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Preferred stock convertible, shares							625
At The Market Offering [Member] | Common Stock [Member]
Subsidiary, Sale of Stock [Line Items]
Number of issuance of public offering							818,523	861,163
Net proceeds from issuance of stock							$ 5,453,000	$ 4,447,000
Converted preferred stock							831
At The Market Offering [Member] | Warrant [Member]
Subsidiary, Sale of Stock [Line Items]
Warrants outstanding							1,793,983