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Consolidated Statements of Changes in Equity - USD ($)
$ in Thousands
Common Stock [Member]
Series B Convertible Preferred Stock [Member]
Series C Convertible Preferred Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2018 [1] [1] [1] $ 156,355 $ (147,592) $ 8,763
Balance, shares at Dec. 31, 2018 768,615 17,303 61,423      
Net loss (10,040) (10,040)
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants, net of issuance costs [1] 6,335 6,335
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants, net of issuance costs, shares 3,039,161          
Conversion of Series C Convertible Preferred Stock to common shares [1] [1] [1] [1] [2]
Conversion of Series C Convertible Preferred Stock to common shares, shares 38,614 (27,053)      
Share-based compensation related to restricted stock , restricted stock units and stock options award, net of forfeitures of shares [1] [1] [1] 325 325
Share-based compensation related to restricted stock , restricted stock units and stock options award, net of forfeitures of shares, shares 69,744          
Balance at Dec. 31, 2019 [1] [1] [1] 163,015 (157,632) 5,383
Balance, shares at Dec. 31, 2019 3,916,134 17,303 34,370      
Net loss (10,544) (10,544)
Conversion of Series C Convertible Preferred Stock to common shares [1] [1] [1]
Conversion of Series C Convertible Preferred Stock to common shares, shares 372,173 (32,027)      
Share-based compensation related to restricted stock , restricted stock units and stock options award, net of forfeitures of shares [1] 606 606
Share-based compensation related to restricted stock , restricted stock units and stock options award, net of forfeitures of shares, shares 2,726,165      
Exercise of pre-funded warrants $ 2 16 18
Exercise of pre-funded warrants, shares 14,856,400      
Settlement of restricted stock units in shares of common stock [1] [1]
Settlement of restricted stock units in shares of common stock, shares 165,000      
Issuance of common shares, including at the market offering net of issuance costs $ 3 15,197 15,200
Issuance of common shares, including at the market offering net of issuance costs, shares 24,108,771      
Exercise of Warrants F [1] 1,418 1,418
Exercise of Warrants F, shares 2,866,600      
Exercise of Unit Purchase Option [1] 82 82
Exercise of Unit Purchase Option, shares 253,587      
Balance at Dec. 31, 2020 $ 5 [1] [1] [1] $ 180,334 $ (168,176) $ 12,163
Balance, shares at Dec. 31, 2020 49,264,830 17,303 2,343      
[1] Represents an amount less than $1
[2] Represents an amount less than $1 thousand