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Equity (Details Narrative) - USD ($)
2 Months Ended 6 Months Ended 12 Months Ended
Dec. 16, 2019
Sep. 19, 2019
Apr. 12, 2019
Apr. 08, 2019
Jul. 03, 2018
Jul. 02, 2018
Jun. 28, 2018
Apr. 02, 2018
Mar. 28, 2018
Mar. 02, 2018
Feb. 26, 2018
Feb. 21, 2018
Feb. 21, 2018
Feb. 07, 2018
Dec. 02, 2017
Feb. 28, 2018
Jun. 30, 2018
Dec. 31, 2019
Mar. 27, 2019
Dec. 31, 2018
Apr. 04, 2019
Jun. 29, 2018
Mar. 31, 2018
Mar. 27, 2018
Dec. 31, 2017
Common stock, par value                                   $ 0.0001   $ 0.0001          
Common stock, shares issued                                   3,916,134   768,615          
Common stock, shares outstanding                                   3,916,134   768,615          
Shares issued during the period new issue value                                   $ 6,335,000   $ 15,827,000          
Fair value of embedded derivative                             $ 66,000                    
Number of warrants to purchase common stock                                   4,016,817              
Gross proceeds from offering, cost   $ 5,000,000                                              
Warrant exercise price                                   $ 22.95              
Conversion stock shares converted                                   677,342              
Common stock shares authorized                                   150,000,000   150,000,000          
Accretion of the redeemable preferred shares                                       $ (438,000)          
Debt instrument, description   On September 19, 2019, the Company entered into an underwriting agreement relating to an underwritten public offering (the "September 2019 Offering") of (i) 539,000 common units ("2019 Common Units"), with each 2019 Common Unit being comprised of one share of the Company's common stock and one Series E warrant (collectively, the "Series E Warrants") to purchase one share of common stock and (ii) 2,238,777 pre-funded units ("2019 Pre-Funded Units"), with each 2019 Pre-Funded Unit being comprised of one pre-funded warrant (collectively, the "2019 Pre-Funded Warrants") to purchase one share of common stock and one Series E Warrant, which closed on September 24, 2019. The offering price to the public was $1.80 per 2019 Common Unit and $1.79 per 2019 Pre-Funded Unit. In connection with this public offering, on September 24, 2019, the underwriter partially exercised its over-allotment option and purchased an additional Series E Warrants to purchase 194,444 shares of common stock at a purchase price of $0.01 per Series E Warrant.                                              
Capital stock shares authorized                                   155,000,000              
Capital stock par value                                   $ 0.0001              
Weighted average of the remaining contractual life                                   5 years 10 months 6 days              
Aggregate intrinsic value of the total exercisable warrants and options                                   $ 2              
April 2019 Underwriter Warrants [Member]                                                  
Warrant exercise price       $ 6.25                                          
Percentage for gross proceeds of offering       125.00%                                          
Pre-fund warrants description       The April 2019 Underwriter Warrants are exercisable at any time and from time to time, in whole or in part, following the date of issuance and ending on April 4, 2024, at an exercise price of $6.25 per share (125% of the offering price to the public per share).                                          
2019 Common Units [Member]                                                  
Common units, shares   539,000                                              
Share price   $ 1.80                                              
2019 Pre-Funded Units [Member]                                                  
Warrant exercise price   $ 0.01                                              
Common units, shares   2,238,777                                              
Share price   $ 1.79                                              
2019 Pre-Funded Units and Pre-Funded Warrants [Member]                                                  
Shares issued during the period new issue                                   2,000,811              
Shares issued during the period new issue value                                   $ 35,705              
Number of warrants to purchase common stock                                   2,000,811              
Outstanding pre-funded warrants are exercisable into shares of common stock                                   270,000              
Pre-Funded Warrants [Member]                                                  
Shares issued during the period new issue                                       417,606          
Shares issued during the period new issue value                                       $ 208,803          
Number of warrants to purchase common stock                                       20,880,250          
Outstanding pre-funded warrants are exercisable into shares of common stock                                       32,034          
Employee and Non-employee Stock Options [Member]                                                  
Weighted average of the remaining contractual life                                   10 months 28 days              
Unvested stock-based compensation                                       $ 126,000          
Series D Purchase Agreement [Member]                                                  
Convertible preferred stock conversion price per share                   $ 150.00                              
Sale of stock stated value per share, description                         Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis (subject to the beneficial ownership limitation set forth in the certificate of designation for the Series C Convertible Preferred Stock).                        
Sale of stock, offering percentage                         15.00%                        
SPA Amendment [Member]                                                  
Shares issued during the period new issue value                       $ 3,200,000                          
Fair value of embedded derivative                       620,000 $ 620,000                        
Amount of redeemable preferred stock                       $ 2,580,000                          
Letter Agreement [Member]                                                  
Accretion of the redeemable preferred shares                                 $ 438,000                
Underwriter Warrants [Member]                                                  
Number of warrants to purchase common stock   194,444                                              
Sale of stock, offering percentage   7.00%                                              
Warrant exercise price   $ 2.25                                              
Percentage for shares of common stock sold   125.00%                                              
Pre-fund warrants description   The September 2019 Underwriter Warrants are exercisable at any time and from time to time, in whole or in part, following the date of issuance and ending on September 19, 2024, at an exercise price of $2.25 per share (125% of the offering price to the public per 2019 Common Unit).                                              
Series A Warrants [Member]                                                  
Number of warrants to purchase common stock                               31                  
Common Stock [Member]                                                  
Shares issued during the period new issue                   20,000               3,039,161   711,777          
Shares issued during the period new issue value [1]                                              
Gross proceeds from offering, cost                   $ 3,000,000                              
Stock issued price per shares                                             $ 150.00    
Accretion of the redeemable preferred shares                                                
Number of redeemable preferred stock                                                
Underwriter Warrants [Member]                                                  
Number of warrants to purchase common stock                   1,200                              
Offering description                   The Company issued to the underwriter warrants to purchase up to 1,200 shares of common stock, or 6% of the number of shares of common stock sold in the March 2018 Offering (the "March Underwriter Warrants"). The March Underwriter Warrants are exercisable at any time and from time to time, in whole or in part, following the date of issuance and ending February 27, 2023, at a price per share equal to $187.50 (125% of the offering price to the public per share).                              
Warrant exercise price                   $ 187.50                              
Percentage for shares of common stock sold               6.00%   6.00%                              
Percentage for gross proceeds of offering               125.00%   125.00%                              
Series D Warrants [Member]                                                  
Common units, per share                                   $ 15.00              
Pre-funded units, per share                                   $ 15.00              
Stock expiration term                                   5 years              
Pre-fund warrants description                                   Each Pre-Funded Warrant contained in a Pre-Funded Unit is exercisable for 0.02 share of our common stock at an exercise price of $0.01 per share. The Pre-Funded Warrants are immediately exercisable and may be exercised at any time until all of the Pre-Funded Warrants are exercised in full.              
Warrant [Member]                                                  
Number of warrants to purchase common stock       34,955                                          
Sale of stock, offering percentage       7.00%                                          
Maximum [Member] | Underwriter Warrants [Member]                                                  
Number of warrants to purchase common stock               3,429                                  
Stock issued price per shares               $ 109.38                                  
Series D Investor [Member] | Series D Purchase Agreement [Member]                                                  
Gross proceeds from offering, cost               $ 300,000                                  
Series D Investor [Member] | Waiver Agreement [Member]                                                  
Sale of stock, offering percentage                     15.00%                            
Gross proceeds from offering, cost                     $ 7,000,000                            
Offering description                     (i) the Series D Exchange Right, which was provided by the original SPA, would not be applicable to an offering of up to $7,000,000 which occurred no later than March 9, 2018, (ii) the Company shall reduce the conversion price of the Series D Preferred Stock to the public offering price of our common stock in such offering, and (iii) instead of using 15% of the proceeds from such offering to redeem shares of Series C Convertible Preferred Stock held by the Series D Investor, which was provided by the February 2018 SPA amendment, the Company was required to use 15% of the proceeds from such offering to redeem a portion of the outstanding shares of Series D Preferred Stock held by the Series D Investor at a per share purchase price equal to the stated value of the Series D Preferred Stock.                            
Series D Investor [Member] | Letter Agreement [Member]                                                  
Sale of stock stated value per share, description             Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis, all outstanding shares of Series C Convertible Preferred Stock held by the Series D Investor will be redeemed at a per share purchase price equal to the stated value of the Series C Convertible Preferred Stock, and (ii) all outstanding shares of Series D Preferred Stock will be redeemed at a per share purchase price equal to the stated value of the Series D Preferred Stock.                                    
Series C Investor [Member] | Waiver Agreement [Member]                                                  
Sale of stock, offering percentage                     15.00%                            
July 2016 Public Offering [Member]                                                  
Number of exercised options to purchase shares                               13,508                  
Public Offering [Member]                                                  
Shares issued during the period new issue               57,143                                  
Gross proceeds from offering, cost               $ 5,000,000                                  
Stock issued price per shares               $ 87.50                                  
Qualified Offering [Member] | Series D Investor [Member]                                                  
Due from affiliates             $ 3,000,000                                    
July 2018 Offering [Member]                                                  
Gross proceeds from offering, cost           $ 9,800,000                                      
July 2018 Offering [Member] | Letter Agreement [Member]                                                  
Amount utilized for redemption of outstanding shares         $ 2,264,269                                        
Number of redeemable preferred stock         306,917                                        
July 2018 Offering [Member] | Underwriting Agreement [Member]                                                  
Number of warrants to purchase common stock                                           100,000      
Warrant exercise price                                           $ 14.50      
Common units, shares                                           217,029      
Pre-funded units, shares                                           449,640      
Common units, per share                                           $ 15.00      
Pre-funded units, per share                                           14.50      
Underwriting discount and commission price per shares                                           $ 1.015      
July 2018 Offering [Member] | Common Stock [Member] | Underwriting Agreement [Member]                                                  
Number of warrants to purchase common stock                                           100,000      
July 2018 Offering [Member] | Underwriter Warrants [Member]                                                  
Stock issued price per shares           $ 18.75                                      
Percentage for shares of common stock sold           6.00%                                      
Percentage for gross proceeds of offering           125.00%                                      
July 2018 Offering [Member] | Series D Warrants [Member] | Underwriting Agreement [Member]                                                  
Number of warrants to purchase common stock                                           100,000      
Underwriting discount and commission price per shares                                           $ 0.035      
July 2018 Offering [Member] | Maximum [Member] | Underwriter Warrants [Member]                                                  
Number of warrants to purchase common stock           40,000                                      
July 2018 Offering [Member] | Maximum [Member] | Series D Warrants [Member] | Underwriting Agreement [Member]                                                  
Common stock, par value                                           $ 0.50      
Number of warrants to purchase common stock                                           100,000      
Common stock shares authorized                                           100,000      
Underwritten Public Offering [Member]                                                  
Shares issued during the period new issue     12,393 486,957                                          
Gross proceeds from offering, cost     $ 47,000 $ 2,000,000                                          
Stock issued price per shares     $ 5.00 $ 5.00                                          
Series B Convertible Preferred Stock [Member]                                                  
Preferred stock, shares outstanding                                   17,303              
Convertible preferred stock shares issued upon conversion                                   555,138              
Shares issued during the period new issue                                   442,424              
Convertible preferred stock conversion price per share                                   $ 1.80              
Number of exercised options to purchase shares                               13,508                  
Proceeds from placement agent                               $ 557,205                  
Series C Convertible Preferred Stock [Member]                                                  
Preferred stock, shares outstanding                                   34,370              
Convertible preferred stock shares issued upon conversion                                   122,204              
Shares issued during the period new issue                                   1,069,822              
Convertible preferred stock conversion price per share                                   $ 1.80              
Series D Convertible Preferred Stock [Member]                                                  
Preferred stock, shares outstanding                                                
Convertible preferred stock shares issued upon conversion                                                
Shares issued during the period new issue                                                
Series D Convertible Preferred Stock [Member] | Redemption Obligation [Member]                                                  
Gross proceeds from offering, cost percentage                             12.50%                    
Shares issued during the period new issue value                             $ 1,000,000                    
Series D Convertible Preferred Stock [Member] | Redemption Obligation [Member] | Maximum [Member]                                                  
Shares issued during the period new issue value                             1,500,000                    
Series D Convertible Preferred Stock [Member] | Private Placements [Member]                                                  
Proceeds from sale of stock                             $ 750,000                    
Sale of stock stated value per share, description                                       The SPA contains a "most favored nation" provision, which provides that, until the Company consummates a "Qualified Offering", in the event the Company undertakes, or enter into any agreement to undertake, the issuance and sale of common stock and/or common stock equivalents to third party investors for cash (a "Subsequent Financing"), the Series D Investor may elect, in its sole discretion, to exchange all or some of the Series D Preferred Stock then held by such investor for any securities or units issued in such Subsequent Financing on a $1.00 per stated value for $1.00 new subscription amount basis (the "MFN Adjustment").          
Series D Convertible Preferred Stock [Member] | Private Placements [Member] | Investor [Member]                                                  
Sale of stock stated value per share, description                             The Series D Investor also had the option to exchange their Series D Preferred Stock into the securities issued in a Qualified Offering upon consummation of a Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis.                    
Redeemable Preferred Shares [Member]                                                  
Percentage for common stock outstanding                             20.00%                    
Fair value of embedded derivative                             $ 934,000                    
Series B Preferred Stock [Member]                                                  
Preferred stock, shares outstanding                                   17,303   17,303   17,303      
Convertible preferred stock shares issued upon conversion                               2,229           55,197      
Convertible preferred stock conversion price per share                                           $ 15.00      
Series D Preferred Stock [Member]                                                  
Preferred stock, shares outstanding               300                                  
Convertible preferred stock shares issued upon conversion               1,429                                  
Convertible preferred stock conversion price per share               $ 87.50                                  
Preferred stock description               The fair value increased substantially, i.e by more than 10%, the change in terms was accounted for as an extinguishment.   The fair value increased substantially, i.e by more than 10%, the change in terms was accounted for as an extinguishment.                              
Changes in carrying amount               $ 32,000   $ 49,000                              
Series D Preferred Stock [Member] | SPA Amendment and Waiver Agreement [Member]                                                  
Convertible preferred stock conversion price per share               $ 150.00   $ 350.00                              
Offering description                   15% of the gross proceeds from the March 2018 Offering                              
Payments to acquire shares                   $ 450,000                              
Number of shares purchased                   450                              
Series D Preferred Stock [Member] | March 2018 Offering [Member]                                                  
Preferred stock, shares outstanding                   750                              
Convertible preferred stock shares issued upon conversion                   2,857                              
Convertible preferred stock conversion price per share                   $ 150.00                              
Series B Convertible Preferred Stock [Member]                                                  
Preferred stock, shares outstanding                                   17,303              
Conversion stock shares converted [2]                                   555,138              
Series B Convertible Preferred Stock [Member] | March 2018 Offering [Member]                                                  
Preferred stock, shares outstanding                   17,303                              
Convertible preferred stock shares issued upon conversion                   3,807                              
Convertible preferred stock conversion price per share                   $ 150.00                              
Series B Convertible Preferred Stock [Member] | April 2018 Offering [Member]                                                  
Preferred stock, shares outstanding                 17,303                                
Convertible preferred stock shares issued upon conversion                 4,759                                
Convertible preferred stock conversion price per share                 $ 87.50                                
Series C Convertible Preferred Stock [Member]                                                  
Preferred stock, shares outstanding                                   34,370              
Conversion stock shares converted                                   122,204              
Series C Convertible Preferred Stock [Member] | March 2018 Offering [Member]                                                  
Preferred stock, shares outstanding                   741,651                              
Convertible preferred stock shares issued upon conversion                   18,082                              
Convertible preferred stock conversion price per share                   $ 150.00                              
Series C Convertible Preferred Stock [Member] | April 2018 Offering [Member]                                                  
Preferred stock, shares outstanding                 451,695                                
Convertible preferred stock shares issued upon conversion                 13,766                                
Convertible preferred stock conversion price per share                 $ 87.50                                
Series C Preferred Stock [Member]                                                  
Preferred stock, shares outstanding   37,025                               34,370   61,423   378,840      
Convertible preferred stock shares issued upon conversion   84,253                                       133,929      
Convertible preferred stock conversion price per share   $ 1.80                                       $ 15.00      
Series C Preferred Stock [Member] | Series D Investor [Member] | Series D Purchase Agreement [Member]                                                  
Conversion stock shares converted               46,875                                  
Series C Preferred Stock [Member] | Series D Investor [Member] | Second Waiver Agreement [Member] | Planned April 2018 Offering [Member]                                                  
Gross proceeds from offering, cost                 $ 5,000,000                                
Offering description                 (i) the Series D Exchange Right, which was provided by the original SPA, would not be applicable to a subsequent financing consisting solely of shares of common stock, which shall be publicly registered on Form S-3 for gross proceeds to us of up to $5,000,000, to be consummated by not later than April 3, 2018 (the "Planned April 2018 Offering"), (ii) the Company's obligation to use 15% of the proceeds from any subsequent offering of our securities that is not a Qualified Offering to redeem the outstanding shares of the Series C Convertible Preferred Stock held by the Series D Investor, which was provided by the February 2018 SPA amendment, would not be applicable to the Planned April 2018 Offering, (iii) the Company shall reduce the conversion price of the Series D Preferred Stock to the public offering price of our common stock sold in the Planned April 2018 Offering, and (iv) the Company shall use $300,000 of the proceeds from the Planned April 2018 Offering to redeem outstanding shares of Series C Convertible Preferred Stock held by the Series D Investor at a per share purchase price equal to the stated value of the Series C Convertible Preferred Stock.                                
Amount utilized for redemption of outstanding shares                 $ 300,000                                
Series B Convertible Preferred Stock [Member]                                                  
Preferred stock, shares outstanding   17,303                                     17,303        
Convertible preferred stock shares issued upon conversion   355,288                                     133,233        
Convertible preferred stock conversion price per share   $ 1.80                                              
Debt instrument, conversion price                                         $ 5.00        
Series B Convertible Preferred Stock [Member] | Qualified Offering [Member]                                                  
Sale of stock stated value per share, description           Series B Convertible Preferred Stock into securities issued in a Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis upon a Qualified Offering.                                      
Series D Preferred Stock [Member] | July 2018 Offering [Member]                                                  
Number of redeemable preferred stock         300                                        
Series C Convertible Preferred Stock One [Member]                                                  
Preferred stock, shares outstanding                                         59,423        
Convertible preferred stock shares issued upon conversion                                         50,708        
Debt instrument, conversion price                                         $ 5.00        
Series E Warrants [Member]                                                  
Number of warrants to purchase common stock                                   2,972,221              
Warrant exercise price                                   $ 1.80              
Series E Warrants [Member] | 2019 Common Units [Member]                                                  
Warrant exercise price   $ 1.80                                              
Warrant exercise term   5 years                                              
Series E Warrants [Member] | 2019 Pre-Funded Units [Member]                                                  
Warrant exercise price   $ 1.80                                              
Warrant exercise term   5 years                                              
Restricted Stock [Member] | Chief Executive Officer [Member]                                                  
Stock option granted 165,000                                 70,582   0          
Stock option vesting period                                   3 years   3 years          
Fair value of stock option $ 141,900                                 $ 668,000   $ 668,000          
Restricted Stock [Member] | Employees and Directors [Member]                                                  
Stock option granted                                   70,582   0          
Stock option vesting period                                   3 years   3 years          
Fair value of stock option                                   $ 668,000   $ 668,000          
Secretary of State of Delaware a Certificate of Amendment [Member]                                                  
Reverse stock split                           one-for-thirty-five reverse stock split.         one-for-thirty-five reverse stock split.            
Common stock, par value                           $ 0.0001                   $ 0.0001  
Common stock, shares issued                           30,000           38,400,000       769,000 1,500,000
Common stock, shares outstanding                           30,000           38,400,000       769,000 1,500,000
[1] Represents an amount less than $1 thousand
[2] Including the shares of common stock the holders of Series B Convertible Preferred Stock are entitled to receive as cumulative dividends at the rate per share of 15% per annum of the stated value for five years, payable in cash or common stock, at the Company's discretion, but excluding effect of future conversion price adjustment, if any.