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Consolidated Statements of Changes in Equity (Unaudited) - USD ($)
$ in Thousands
Series B Preferred Stock [Member]
Series C Preferred Stock [Member]
Series D Preferred Stock [Member]
Series B Convertible Preferred Stock [Member]
Series C Convertible Preferred Stock [Member]
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2017 [1] [1] [1]     [1] $ 143,079 $ (140,352) $ 2,727
Balance, shares at Dec. 31, 2017 27,075 741,651 750     30,106      
Net loss (5,027) (5,027)
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants     [1] 15,809   15,809
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants, shares           677,477      
Redemption of Series D Preferred Stock     [1]       (750)   (750)
Redemption of Series D Preferred Stock, shares     (750)            
Conversion of Series B Preferred Stock to common shares [1]         [1] 274   274
Conversion of Series B Preferred Stock to common shares, shares (9,772)         1,613      
Conversion of Series C Preferred Stock to common shares   [1]       [1] 936   936
Conversion of Series C Preferred Stock to common shares, shares   (326,436)       22,896      
Exercise of Unit Purchase Option           [1] 557   557
Exercise of Unit Purchase Option, shares           2,229      
Accretion of redeemable preferred shares             (438)   (438)
Redemption of Series C Preferred Stock   [1]         (3,200)   (3,200)
Redemption of Series C Preferred Stock, shares   (353,792)              
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares             64   64
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares, shares           (4)      
Balance at Sep. 30, 2018 [1] [1] [1]     [1] 156,331 (145,379) 10,952
Balance, shares at Sep. 30, 2018 17,303 61,423     734,317      
Balance at Jun. 30, 2018 [1] [1] [1]     [1] 147,466 (143,368) 4,098
Balance, shares at Jun. 30, 2018 17,303 378,840 300     129,505      
Net loss               (2,011) (2,011)
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants           [1] 8,867   8,867
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants, shares           600,334      
Redemption of Series D Preferred Stock     [1]        
Redemption of Series D Preferred Stock, shares     (300)            
Conversion of Series C Preferred Stock to common shares   [1]       [1]  
Conversion of Series C Preferred Stock to common shares, shares   (10,500)       4,480      
Redemption of Series C Preferred Stock   [1]          
Redemption of Series C Preferred Stock, shares   (306,917)              
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares           [1] (2) (2)
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares, shares           (2)      
Balance at Sep. 30, 2018 [1] [1] [1]     [1] 156,331 (145,379) 10,952
Balance, shares at Sep. 30, 2018 17,303 61,423     734,317      
Balance at Dec. 31, 2018       [1] [1] [1] 156,355 (147,592) 8,763
Balance, shares at Dec. 31, 2018       17,303 61,423 768,615      
Net loss               (7,483) (7,483)
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants           [1] 6,331   6,331
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants, shares           2,588,828      
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares           [1] 285   285
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares, shares           69,744      
Conversion of Series C Convertible Preferred Stock to common shares [1]                
Conversion of Series C Convertible Preferred Stock to common shares, shares         (24,554) 29,728      
Balance at Sep. 30, 2019       [1] [1] [1] 162,971 (155,075) 7,896
Balance, shares at Sep. 30, 2019       17,303 36,869 3,456,915      
Balance at Jun. 30, 2019       [1] [1] [1] 158,579 (153,005) 5,574
Balance, shares at Jun. 30, 2019       17,303 38,806 1,397,133      
Net loss (2,070) (2,070)
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants           [1] 4,285   4,285
Issuance of common shares, warrants, pre-funded warrants and exercise of pre-funded warrants, shares           2,057,444      
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares           [1] 107 107
Share-based compensation related to restricted stock and stock options award, net of forfeitures of shares, shares           (142)      
Conversion of Series C Convertible Preferred Stock to common shares [1]                
Conversion of Series C Convertible Preferred Stock to common shares, shares         (1,937) 2,480      
Balance at Sep. 30, 2019       [1] [1] [1] $ 162,971 $ (155,075) $ 7,896
Balance, shares at Sep. 30, 2019       17,303 36,869 3,456,915      
[1] Represents an amount less than $1 thousand