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Equity (Details Narrative) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended
Apr. 12, 2019
Apr. 08, 2019
Apr. 04, 2019
Mar. 27, 2019
Jun. 30, 2019
Feb. 04, 2019
Dec. 31, 2018
Common stock, par value         $ 0.0001   $ 0.0001
Outstanding pre-funded warrants are exercisable into shares of common stock            
Number of shares converted         249,522    
Number of warrants to purchase common stock         850,152    
Capital stock shares authorized         155,000,000    
Capital stock par value         $ 0.0001    
Common stock shares authorized         150,000,000   150,000,000
Warrants exercise price per share         $ 101.62    
Underwritten Public Offering [Member]              
Proceeds from common stock shares issued   $ 2,000          
Underwritten public offering shares of common stock   486,957          
Shares issued price per share   $ 5.00          
Over-Allotment Option [Member]              
Number of common stock shares issued 12,393            
Proceeds from common stock shares issued $ 47            
Shares issued price per share $ 5.00            
Long Term Incentive Plan [Member]              
Increase in common stock shares issuable           500,000  
Series C Convertible Preferred Stock [Member]              
Number of shares converted         22,617    
Additional shares of common stock issuable upon conversion     50,708        
Preferred stock shares outstanding     59,423        
Series B and Series C Convertible Preferred Stock [Member]              
Conversion price of outstanding shares   $ 5.00          
Series B Convertible Preferred Stock [Member]              
Additional shares of common stock issuable upon conversion     133,233        
Preferred stock shares outstanding     17,303        
Common Stock [Member]              
Number of common stock shares issued         32,034    
Exercise of pre-funded warrants, shares         32,034    
Proceeds from common stock shares issued         $ 16    
Number of shares converted         27,248    
Preferred Stock Blank Check [Member]              
Preferred stock shares authorized         5,000,000    
April Underwriter Warrants [Member]              
Number of warrants to purchase common stock   34,955          
Shares sold in offering percentage   7.00%          
Warrants maturity date   Apr. 04, 2024          
Warrants exercise price per share   $ 6.25          
Offering price percentage   125.00%          
Secretary of State of Delaware a Certificate of Amendment [Member]              
Reverse stock split       one-for-fifty reverse stock split      
Common stock, par value       $ 0.0001