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Equity (Details Narrative) - USD ($)
$ / shares in Units, $ in Thousands
2 Months Ended 6 Months Ended 12 Months Ended
Jul. 03, 2018
Jul. 02, 2018
Jun. 28, 2018
Apr. 02, 2018
Mar. 28, 2018
Mar. 02, 2018
Feb. 26, 2018
Feb. 21, 2018
Feb. 21, 2018
Feb. 07, 2018
Jan. 08, 2018
Dec. 02, 2017
Mar. 14, 2017
Mar. 08, 2017
Jul. 07, 2016
Mar. 28, 2011
Feb. 28, 2018
Jun. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Oct. 24, 2018
Jun. 29, 2018
Mar. 31, 2018
Nov. 28, 2017
Sep. 28, 2016
May 24, 2016
Sep. 09, 2015
Dec. 16, 2013
Common stock, par value                                     $ 0.0001 $ 0.0001                
Common stock, shares issued                                     38,408,953 1,483,556                
Common stock, shares outstanding                                     38,408,953 1,483,556                
Number of warrants to purchase common stock                                     40,746,189                  
Conversion stock shares converted                                     4,641,185                  
Warrant exercise price                                     $ 1.25                  
Shares issued during the period new issue value                                     $ 15,827                  
Fair value of embedded derivative                       $ 66                                
Common stock shares authorized                                     150,000,000 150,000,000                
Accretion of the redeemable preferred shares                                     $ (438)                  
Aggregate intrinsic value of the total exercisable warrants and options                                     $ 1                  
Outstanding pre-funded warrants are exercisable into shares of common stock                                     1,601,666                  
Capital stock shares authorized                                     155,000,000                  
Capital stock par value                                     $ 0.0001                  
Weighted average of the remaining contractual life                                     7 years 6 months 25 days                  
Weighted average exercise price                                       $ 24.85                
Umbrella Plan [Member]                                                        
Stock option plan expiration date                               Mar. 27, 2021                        
Number of common stock awards reserve for future issuance                               572     310                  
Employee and Non-employee Stock Options [Member]                                                        
Weighted average of the remaining contractual life                                     6 months 18 days                  
Unvested stock-based compensation                                     $ 38                  
Chief Executive Officer [Member]                                                        
Stock option granted                                     0 118                
Exercise price range lower limit                                     $ 24.85 $ 24.85                
Exercise price range upper limit                                     $ 34.65 $ 34.65                
Stock option vesting period                                     3 years 3 years                
Fair value of stock option                                     $ 3 $ 3                
Chief Executive Officer [Member] | 2013 Plan [Member]                                                        
Number of common stock awards reserve for future issuance                                     8,910,610                 572
Stock option vested number of grant, shares                                     8,919,737   8,900,000       7,200 11,428 537  
Employees and Directors [Member]                                                        
Stock option granted                                     0 118                
Exercise price range lower limit                                     $ 24.85 $ 24.85                
Exercise price range upper limit                                     $ 34.65 $ 34.65                
Stock option vesting period                                     3 years 3 years                
Fair value of stock option                                     $ 3 $ 3                
Series D Purchase Agreement [Member]                                                        
Convertible preferred stock conversion price per share           $ 3.00                                            
Sale of stock stated value per share, description               Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis (subject to the beneficial ownership limitation set forth in the certificate of designation for the Series C Preferred Stock).                                        
Sale of stock, offering percentage               15.00%                     15.00%                  
Series D Purchase Agreement [Member] | Series D Investor [Member]                                                        
Gross proceeds from offering, cost       $ 300                                                
SPA Amendment [Member]                                                        
Shares issued during the period new issue value                 $ 3,200                                      
Fair value of embedded derivative               $ 620 620                                      
Amount of redeemable preferred stock                 $ 2,580                                      
Waiver Agreement [Member] | Series D Investor [Member]                                                        
Gross proceeds from offering, cost             $ 7,000                                          
Sale of stock, offering percentage             15.00%                                          
Offering description             (i) the Series D Exchange Right would not be applicable to an offering of up to $7,000,000 which occurred no later than March 9, 2018, (ii) the Company shall reduce the conversion price of the Series D Preferred Stock to the public offering price of our common stock in such offering, and (iii) instead of using 15% of the proceeds from such offering to redeem shares of Series C Preferred Stock held by the Series D Investor, the Company shall use 15% of the proceeds from such offering to redeem a portion of the outstanding shares of Series D Preferred Stock held by the Series D Investor at a per share purchase price equal to the stated value of the Series D Preferred Stock.                                          
Letter Agreement [Member]                                                        
Accretion of the redeemable preferred shares                                   $ 438                    
Letter Agreement [Member] | Series D Investor [Member]                                                        
Sale of stock stated value per share, description     Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis, all outstanding shares of Series C Preferred Stock held by the Series D Investor will be redeemed at a per share purchase price equal to the stated value of the Series C Preferred Stock                                                  
Series A Warrants [Member]                                                        
Number of warrants to purchase common stock                                 1,545                      
Common Stock [Member]                                                        
Shares issued during the period new issue           1,000,000                         35,588,810                  
Gross proceeds from offering, cost           $ 3,000                                            
Shares issued during the period new issue value                                     $ 4                  
Stock issued price per shares                                             $ 3.00          
Accretion of the redeemable preferred shares                                                      
Number of redeemable preferred stock                                                      
Underwriter Warrants [Member]                                                        
Number of warrants to purchase common stock           60,000                                            
Warrant exercise price           $ 3.75                                            
Offering description           The Company issued to the underwriter warrants to purchase up to 60,000 shares of common stock, or 6% of the number of shares of common stock sold in the offering (the March Underwriter Warrants). The March Underwriter Warrants are exercisable at any time and from time to time, in whole or in part, following the date of issuance and ending February 27, 2023, at a price per share equal to $3.75 (125% of the offering price to the public per share).                                            
Percentage for shares of common stock sold       6.00%   6.00%                                            
Percentage for gross proceeds of offering       125.00%   125.00%                                            
Series D Warrants [Member]                                                        
Common units, per share                                     $ 0.30                  
Pre-funded units, per share                                     $ 0.30                  
Warrant [Member]                                                        
Shares issued during the period new issue                                     20,880,250                  
Shares issued during the period new issue value                                     $ 208,803                  
Exercise of pre-funded warrants                                     20,880,250                  
Preferred Stock Blank Check [Member]                                                        
Preferred stock shares authorized                                     5,000,000                  
Maximum [Member] | Underwriter Warrants [Member]                                                        
Number of warrants to purchase common stock       171,429                                                
Stock issued price per shares       $ 2.1875                                                
March 2017 Offering [Member]                                                        
Gross proceeds from offering, cost                         $ 6,800                              
Gross proceeds from offering, cost percentage                         8.00%                              
July 2016 Offering [Member]                                                        
Number of exercised options to purchase shares                                 13,508                      
Public Offering [Member]                                                        
Shares issued during the period new issue       2,857,143                                                
Gross proceeds from offering, cost       $ 5,000                                                
Stock issued price per shares       $ 1.75                                                
Qualified Offering [Member] | Series D Investor [Member]                                                        
Due from affiliates     $ 3,000                                                  
July 2018 Offering [Member]                                                        
Gross proceeds from offering, cost $ 9,800                                                      
July 2018 Offering [Member] | Letter Agreement [Member]                                                        
Amount utilized for redemption of outstanding shares $ 2,264,269                                                      
July 2018 Offering [Member] | Underwriting Agreement [Member]                                                        
Common stock, par value                                           $ 0.0001            
Number of warrants to purchase common stock                                           4,999,999            
Warrant exercise price                                           $ 0.29            
Common units, shares                                           10,851,417            
Pre-funded units, shares                                           22,481,916            
Common units, per share                                           $ 0.30            
Pre-funded units, per share                                           0.29            
Underwriting discount and commission price per shares                                           $ 0.0203            
July 2018 Offering [Member] | Common Stock [Member] | Underwriting Agreement [Member]                                                        
Number of warrants to purchase common stock                                           4,999,999            
July 2018 Offering [Member] | Underwriter Warrants [Member]                                                        
Stock issued price per shares $ 0.375                                                      
Percentage for shares of common stock sold 6.00%                                                      
Percentage for gross proceeds of offering 125.00%                                                      
July 2018 Offering [Member] | Series D Warrants [Member] | Underwriting Agreement [Member]                                                        
Number of warrants to purchase common stock                                           4,999,999            
Underwriting discount and commission price per shares                                           $ 0.0007            
July 2018 Offering [Member] | Maximum [Member] | Underwriter Warrants [Member]                                                        
Number of warrants to purchase common stock 2,000,000                                                      
July 2018 Offering [Member] | Maximum [Member] | Series D Warrants [Member] | Underwriting Agreement [Member]                                                        
Common stock, par value                                           $ 0.01            
Number of warrants to purchase common stock                                           4,999,999            
Common stock shares authorized                                           4,999,999            
Secretary of State of Delaware a Certificate of Amendment [Member]                                                        
Reverse stock split                   one-for-thirty-five reverse stock split.                                    
Common stock, par value                   $ 0.0001                                    
Common stock, shares issued                   51,900,000                                    
Common stock, shares outstanding                   1,500,000                                    
Series B Convertible Preferred Stock [Member]                                                        
Preferred stock, shares outstanding                                     17,303                  
Convertible preferred stock shares issued upon conversion                                     3,330,828 284,446                
Shares issued during the period new issue                                     442,424                  
Convertible preferred stock conversion price per share                                     $ 0.30                  
Number of exercised options to purchase shares                                 13,508                      
Proceeds from placement agent                                 $ 557,205                      
Accretion of the redeemable preferred shares                                                      
Number of redeemable preferred stock                                                      
Series B Convertible Preferred Stock [Member] | Maximum [Member]                                                        
Convertible stock price, percentage                                       10.00%                
Series B Convertible Preferred Stock [Member] | July 2016 Offering [Member]                                                        
Preferred stock, shares outstanding                           311,521                            
Shares issued during the period new issue                           258,952                            
Convertible preferred stock conversion price per share                         $ 56.00   $ 288.75       $ 0.30                  
Number of common stock shares sold                             442,424                          
Number of warrants to purchase common stock                             50,620                          
Share price                             $ 33.00                          
Conversion stock shares converted                         0.589   0.114       110                  
Percentage of cumulative dividend rate                                     15.00%                  
Gross proceeds from offering, cost                             $ 14,600         $ 8,000                
Warrant exercise term                                       5 years                
Warrant exercise price                                       $ 175.00                
Option issued to purchase of shares percentage                             3.50%                          
Option issued exercise price percentage                             125.00%                          
Series B Convertible Preferred Stock [Member] | March 2017 Offering [Member]                                                        
Convertible preferred stock conversion price per share                         $ 56.00                              
Series B Convertible Preferred Stock [Member] | Private Placements [Member]                                                        
Convertible preferred stock shares issued upon conversion                       1,306,536                       180,992        
Convertible preferred stock conversion price per share                       $ 7.00                                
Series C Convertible Preferred Stock [Member]                                                        
Preferred stock, shares outstanding                                     61,423                  
Convertible preferred stock shares issued upon conversion                                     1,310,357                  
Shares issued during the period new issue                                     1,069,822                  
Convertible preferred stock conversion price per share                                     $ 0.30                  
Accretion of the redeemable preferred shares                                                      
Number of redeemable preferred stock                                                      
Series C Convertible Preferred Stock [Member] | March 2017 Offering [Member]                                                        
Convertible preferred stock shares issued upon conversion                                     1,310,357                  
Number of common stock shares sold                         1,069,822                              
Share price                                     $ 0.30                  
Conversion stock shares converted                         0.114                              
Warrant exercise price                         $ 6.40                              
Series D Convertible Preferred Stock [Member]                                                        
Preferred stock, shares outstanding                                                      
Convertible preferred stock shares issued upon conversion                                                      
Shares issued during the period new issue                                                      
Series D Convertible Preferred Stock [Member] | Redemption Obligation [Member]                                                        
Gross proceeds from offering, cost percentage                       12.50%                                
Shares issued during the period new issue value                       $ 1,000                                
Series D Convertible Preferred Stock [Member] | Redemption Obligation [Member] | Maximum [Member]                                                        
Shares issued during the period new issue value                       $ 1,500                                
Series D Convertible Preferred Stock [Member] | Private Placements [Member]                                                        
Shares issued during the period new issue                       750                                
Convertible preferred stock conversion price per share                       $ 7.00                                
Conversion stock shares converted                       142.86             42,677                  
Proceeds from sale of stock                       $ 750                                
Shares issued during the period new issue value                       $ 1                                
Common shares outstanding percentage                       20.00%             19.99%                  
Sale of stock stated value per share, description                                     In addition, the SPA contains a "most favored nation" provision, which provides that, until the Company consummates a "Qualified Offering", in the event the Company undertakes, or enter into any agreement to undertake, the issuance and sale of common stock and/or common stock equivalents to third party investors for cash (a "Subsequent Financing"), the Series D Investor may elect, in its sole discretion, to exchange all or some of the Series D Preferred Stock then held by such investor for any securities or units issued in such Subsequent Financing on a $1.00 per stated value for $1.00 new subscription amount basis (the "MFN Adjustment").                  
Series D Convertible Preferred Stock [Member] | Private Placements [Member] | Investor [Member]                                                        
Shares issued during the period new issue value                       $ 1                                
Sale of stock stated value per share, description                       The Series D Investor also had the option to exchange their Series D Preferred Stock into the securities issued in a Qualified Offering upon consummation of a Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis.                                
Series B Warrants [Member]                                                        
Number of warrants to purchase common stock                                     122,269                  
Warrant exercise price                                     $ 70.00                  
Series B Warrants [Member] | March 2017 Offering [Member]                                                        
Number of warrants to purchase common stock                         122,269                              
Warrant exercise price                         $ 70.00                              
Series C Warrants [Member] | March 2017 Offering [Member]                                                        
Number of warrants to purchase common stock                         122,269                              
Gross proceeds from offering, cost percentage                         3.00%                              
Redeemable Preferred Shares [Member]                                                        
Fair value of embedded derivative                       $ 934                                
Series D Convertible Preferred Stock [Member]                                                        
Convertible preferred stock shares issued upon conversion                                       206,105                
Shares issued during the period new issue                     8,295                 8,295                
Series B Convertible Preferred Stock [Member]                                                        
Percentage of cumulative dividend rate                                     15.00%                  
Fair value of embedded derivative                                       $ 0                
Series B Convertible Preferred Stock [Member] | Redemption Obligation [Member] | Maximum [Member]                                                        
Number of preferred shares converted into common stock                     $ 0                 $ 274                
Series B Convertible Preferred Stock [Member] | Qualified Offering [Member]                                                        
Sale of stock stated value per share, description   Series B Convertible Preferred Stock into securities issued in a Qualified Offering on a $1.00 per stated value for $1.00 new subscription amount basis upon a Qualified Offering.                                                    
Series B Preferred Stock [Member]                                                        
Preferred stock, shares outstanding                                     17,303     17,303            
Convertible preferred stock shares issued upon conversion                                 111,443         2,759,829            
Convertible preferred stock conversion price per share                                           $ 0.30            
Conversion stock shares converted [1]                                     3,330,828                  
Series B Preferred Stock [Member] | March 2018 Offering [Member]                                                        
Preferred stock, shares outstanding           17,303                                            
Convertible preferred stock shares issued upon conversion           190,333                                            
Convertible preferred stock conversion price per share           $ 3.00                                            
Series B Preferred Stock [Member] | April 2018 Offering [Member]                                                        
Preferred stock, shares outstanding         17,303                                              
Convertible preferred stock shares issued upon conversion         237,916                                              
Convertible preferred stock conversion price per share         $ 1.75                                              
Series D Preferred Stock [Member]                                                        
Preferred stock, shares outstanding       300                                                
Convertible preferred stock shares issued upon conversion       71,429                                                
Convertible preferred stock conversion price per share       $ 1.75                                                
Preferred stock description       The fair value increased substantially, i.e by more than 10%, the change in terms was accounted for as an extinguishment.   The fair value increased substantially, i.e by more than 10%, the change in terms was accounted for as an extinguishment.                                            
Changes in carrying amount       $ 32   $ 49                                            
Accretion of the redeemable preferred shares                                                      
Number of redeemable preferred stock                                     750                  
Series D Preferred Stock [Member] | SPA Amendment and Waiver Agreement [Member]                                                        
Convertible preferred stock conversion price per share       $ 3.00   $ 7.00                                            
Offering description           15% of the gross proceeds from the offering                                            
Payments to acquire shares           $ 450                                            
Number of shares purchased           450                                            
Series D Preferred Stock [Member] | March 2018 Offering [Member]                                                        
Preferred stock, shares outstanding           750                                            
Convertible preferred stock shares issued upon conversion           142,857                                            
Convertible preferred stock conversion price per share           $ 3.00                                            
Series D Preferred Stock [Member] | July 2018 Offering [Member]                                                        
Number of redeemable preferred stock 300                                                      
Series C Preferred Stock [Member]                                                        
Preferred stock, shares outstanding                                     61,423     378,840            
Convertible preferred stock shares issued upon conversion                                           6,696,448            
Convertible preferred stock conversion price per share                                           $ 0.30            
Conversion stock shares converted                                     1,310,357                  
Series C Preferred Stock [Member] | Series D Purchase Agreement [Member] | Series D Investor [Member]                                                        
Conversion stock shares converted       46,875                                                
Series C Preferred Stock [Member] | Second Waiver Agreement [Member] | Series D Investor [Member] | Planned April 2018 Offering [Member]                                                        
Gross proceeds from offering, cost         $ 5,000                                              
Offering description         (i) the Series D Exchange Right would not be applicable to a subsequent financing consisting solely of shares of common stock, which shall be publicly registered on Form S-3 for gross proceeds to us of up to $5,000,000, to be consummated by not later than April 3, 2018 (the Planned April 2018 Offering), (ii) the Company's obligation to use 15% of the proceeds from any subsequent offering of our securities that is not a Qualified Offering to redeem the outstanding shares of the Series C Preferred Stock held by the Series D Investor would not be applicable to the Planned April 2018 Offering, (iii) the Company shall reduce the conversion price of the Series D Preferred Stock to the public offering price of our common stock sold in the Planned April 2018 Offering, and (iv) the Company shall use $300,000 of the proceeds from the Planned April 2018 Offering to redeem outstanding shares of Series C Preferred Stock held by the Series D Investor at a per share purchase price equal to the stated value of the Series C Preferred Stock.                                              
Amount utilized for redemption of outstanding shares         $ 300                                              
Series C Preferred Stock [Member] | March 2018 Offering [Member]                                                        
Preferred stock, shares outstanding           741,651                                            
Convertible preferred stock shares issued upon conversion           1,497,427                                            
Convertible preferred stock conversion price per share           $ 3.00                                            
Series C Preferred Stock [Member] | April 2018 Offering [Member]                                                        
Preferred stock, shares outstanding         451,695                                              
Convertible preferred stock shares issued upon conversion         688,297                                              
Convertible preferred stock conversion price per share         $ 1.75                                              
Series C Preferred Stock [Member] | July 2018 Offering [Member]                                                        
Number of redeemable preferred stock 306,917                                                      
Restricted Stock [Member] | Employees and Directors [Member]                                                        
Stock option granted                                     0 84                
Stock option vesting period                                     3 years 3 years                
Fair value of stock option                                     $ 3 $ 3                
Restricted Stock [Member] | Chief Executive Officer [Member]                                                        
Stock option granted                                     0 84                
Stock option vesting period                                     3 years 3 years                
Fair value of stock option                                     $ 3 $ 3                
[1] Including the shares of common stock the holders of Series B Convertible Preferred Stock are entitled to receive as cumulative dividends at the rate per share of 15% per annum of the stated value for five years, payable in cash or common stock, at the Company's discretion, but excluding effect of future conversion price adjustment, if any.