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        <title>BLUEPRINT MEDICINES CORP COMMON STOCK</title>
        <cusip>09627Y109</cusip>
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          <isin value="US09627Y1091"/>
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        <balance>8479.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>695617.16000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ALNYLAM PHARMACEUTICALS, INC.</name>
        <lei>529900S3ZI14OWRJII50</lei>
        <title>ALNYLAM PHARMACEUTICALS INC COMMON STOCK</title>
        <cusip>02043Q107</cusip>
        <identifiers>
          <isin value="US02043Q1076"/>
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        <balance>7326.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>858167.64000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>GILEAD SCIENCES, INC.</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>GILEAD SCIENCES INC COMMON STOCK</title>
        <cusip>375558103</cusip>
        <identifiers>
          <isin value="US3755581036"/>
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        <balance>4933.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>331694.92000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>ProQR Therapeutics NV</name>
        <lei>549300NGS2FJGGDBGS06</lei>
        <title>PROQR THERAPEUTICS NV COMMON STOCK</title>
        <cusip>N71542109</cusip>
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          <isin value="NL0010872495"/>
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        <balance>11969.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>102215.26000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Homology Medicines Inc</name>
        <lei>549300RWKPJEFTM3K452</lei>
        <title>HOMOLOGY MEDICINES INC COMMON STOCK</title>
        <cusip>438083107</cusip>
        <identifiers>
          <isin value="US4380831077"/>
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        <balance>9066.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>145056.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Regenxbio Inc</name>
        <lei>549300EOES47LATSET33</lei>
        <title>REGENXBIO INC COMMON STOCK</title>
        <cusip>75901B107</cusip>
        <identifiers>
          <isin value="US75901B1070"/>
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        <balance>10729.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>449115.94000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>SORRENTO THERAPEUTICS, INC.</name>
        <lei>549300RH23PRR3M13410</lei>
        <title>SORRENTO THERAPEUTICS INC COMMON STOCK</title>
        <cusip>83587F202</cusip>
        <identifiers>
          <isin value="US83587F2020"/>
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        <balance>33277.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>97168.84000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Audentes Therapeutics Inc</name>
        <lei>549300PZYT0QC9UNJF13</lei>
        <title>AUDENTES THERAPEUTICS INC COMMON STOCK</title>
        <cusip>05070R104</cusip>
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          <isin value="US05070R1041"/>
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        <balance>13312.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>AGILENT TECHNOLOGIES, INC.</name>
        <lei>QUIX8Y7A2WP0XRMW7G29</lei>
        <title>AGILENT TECHNOLOGIES INC COMMON STOCK</title>
        <cusip>00846U101</cusip>
        <identifiers>
          <isin value="US00846U1016"/>
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        <balance>8770.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Solid Biosciences Inc</name>
        <lei>N/A</lei>
        <title>SOLID BIOSCIENCES INC COMMON STOCK</title>
        <cusip>83422E105</cusip>
        <identifiers>
          <isin value="US83422E1055"/>
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        <balance>9566.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Genscript Biotech Corp</name>
        <lei>529900YIYUOJOXSAE372</lei>
        <title>GENSCRIPT BIOTECH CORP COMMON STOCK</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="KYG3825B1059"/>
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        <balance>290318.00000000</balance>
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        <currencyConditional curCd="HKD" exchangeRt="7.82775000"/>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Editas Medicine Inc</name>
        <lei>5299000AON4Q9NT2JE42</lei>
        <title>EDITAS MEDICINE INC COMMON STOCK</title>
        <cusip>28106W103</cusip>
        <identifiers>
          <isin value="US28106W1036"/>
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        <balance>15368.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Ultragenyx Pharmaceutical Inc</name>
        <lei>529900EV44GVDN1DCX77</lei>
        <title>ULTRAGENYX PHARMACEUTICAL IN COMMON STOCK</title>
        <cusip>90400D108</cusip>
        <identifiers>
          <isin value="US90400D1081"/>
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        <balance>15969.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>633170.85000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>NanoString Technologies Inc</name>
        <lei>549300G4CK0Y3WRDMY89</lei>
        <title>NANOSTRING TECHNOLOGIES INC COMMON STOCK</title>
        <cusip>63009R109</cusip>
        <identifiers>
          <isin value="US63009R1095"/>
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        <balance>11311.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>304492.12000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Intellia Therapeutics Inc</name>
        <lei>5493002T5BCPE5DZC723</lei>
        <title>INTELLIA THERAPEUTICS INC COMMON STOCK</title>
        <cusip>45826J105</cusip>
        <identifiers>
          <isin value="US45826J1051"/>
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        <balance>12083.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>DICERNA PHARMACEUTICALS, INC.</name>
        <lei>549300CTZMJMPH28WN39</lei>
        <title>DICERNA PHARMACEUTICALS INC COMMON STOCK</title>
        <cusip>253031108</cusip>
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          <isin value="US2530311081"/>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Spark Therapeutics Inc</name>
        <lei>549300EZ6EOPQBLJNB93</lei>
        <title>SPARK THERAPEUTICS INC COMMON STOCK</title>
        <cusip>84652J103</cusip>
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          <isin value="US84652J1034"/>
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        <balance>6508.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SANGAMO THERAPEUTICS, INC.</name>
        <lei>2549006WMRKRC4G32Z67</lei>
        <title>SANGAMO THERAPEUTICS INC COMMON STOCK</title>
        <cusip>800677106</cusip>
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          <isin value="US8006771062"/>
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        <balance>37294.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>CRISPR Therapeutics AG</name>
        <lei>506700O6IRRIQLT3W370</lei>
        <title>CRISPR THERAPEUTICS AG COMMON STOCK</title>
        <cusip>H17182108</cusip>
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          <isin value="CH0334081137"/>
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        <balance>9349.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>CH</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>INVITAE CORPORATION</name>
        <lei>549300MYI59DZW1WIX92</lei>
        <title>INVITAE CORP COMMON STOCK</title>
        <cusip>46185L103</cusip>
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          <isin value="US46185L1035"/>
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        <balance>29240.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>581876.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>WAVE Life Sciences Ltd</name>
        <lei>54930070006GPKFYZ813</lei>
        <title>WAVE LIFE SCIENCES LTD COMMON STOCK</title>
        <cusip>Y95308105</cusip>
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        <balance>8586.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>SG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Uniqure NV</name>
        <lei>N/A</lei>
        <title>UNIQURE NV COMMON STOCK</title>
        <cusip>N90064101</cusip>
        <identifiers>
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        <balance>10608.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>590441.28000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>Qiagen N.V.</name>
        <lei>54930036WK3GMCN17Z57</lei>
        <title>QIAGEN N.V. COMMON STOCK</title>
        <cusip>N72482123</cusip>
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        <balance>23366.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>1000064.80000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SAREPTA THERAPEUTICS, INC.</name>
        <lei>549300IKDPIED8J8IG21</lei>
        <title>SAREPTA THERAPEUTICS INC COMMON STOCK</title>
        <cusip>803607100</cusip>
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          <isin value="US8036071004"/>
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        <balance>7818.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>879446.82000000</valUSD>
        <pctVal>4.694280980651</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARROWHEAD PHARMACEUTICALS, INC.</name>
        <lei>549300O3CSB8T7OZ3D66</lei>
        <title>ARROWHEAD PHARMACEUTICALS IN COMMON STOCK</title>
        <cusip>04280A100</cusip>
        <identifiers>
          <isin value="US04280A1007"/>
        </identifiers>
        <balance>16587.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1211016.87000000</valUSD>
        <pctVal>6.464124186712</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ZIOPHARM ONCOLOGY, INC.</name>
        <lei>N/A</lei>
        <title>ZIOPHARM ONCOLOGY INC COMMON STOCK</title>
        <cusip>98973P101</cusip>
        <identifiers>
          <isin value="US98973P1012"/>
        </identifiers>
        <balance>56717.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>295495.57000000</valUSD>
        <pctVal>1.577286087767</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Voyager Therapeutics Inc</name>
        <lei>54930082S4XVR0ZWCC74</lei>
        <title>VOYAGER THERAPEUTICS INC COMMON STOCK</title>
        <cusip>92915B106</cusip>
        <identifiers>
          <isin value="US92915B1061"/>
        </identifiers>
        <balance>7444.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>101536.16000000</valUSD>
        <pctVal>0.541976221753</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Veracyte Inc</name>
        <lei>529900ESWZRHXOW27Z37</lei>
        <title>VERACYTE INC COMMON STOCK</title>
        <cusip>92337F107</cusip>
        <identifiers>
          <isin value="US92337F1075"/>
        </identifiers>
        <balance>14670.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>421322.40000000</valUSD>
        <pctVal>2.248920212187</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BLUEBIRD BIO, INC.</name>
        <lei>N/A</lei>
        <title>BLUEBIRD BIO INC COMMON STOCK</title>
        <cusip>09609G100</cusip>
        <identifiers>
          <isin value="US09609G1004"/>
        </identifiers>
        <balance>7631.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>617653.14000000</valUSD>
        <pctVal>3.296887681897</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BIOMARIN PHARMACEUTICAL INC.</name>
        <lei>NSLL8ITTRR0J5HEMR848</lei>
        <title>BIOMARIN PHARMACEUTICAL INC COMMON STOCK</title>
        <cusip>09061G101</cusip>
        <identifiers>
          <isin value="US09061G1013"/>
        </identifiers>
        <balance>9529.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>769085.59000000</valUSD>
        <pctVal>4.105198603856</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INCORPORATED</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC COMMON STOCK</title>
        <cusip>92532F100</cusip>
        <identifiers>
          <isin value="US92532F1003"/>
        </identifiers>
        <balance>3452.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>765481.00000000</valUSD>
        <pctVal>4.085958147361</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROCKET PHARMACEUTICALS, INC.</name>
        <lei>549300R7VV82YUIN4Y93</lei>
        <title>ROCKET PHARMACEUTICALS INC COMMON STOCK</title>
        <cusip>77313F106</cusip>
        <identifiers>
          <isin value="US77313F1066"/>
        </identifiers>
        <balance>15199.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>267350.41000000</valUSD>
        <pctVal>1.427053820983</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2019-11-30</ncom:dateSigned>
      <ncom:nameOfApplicant>GLOBAL X FUNDS</ncom:nameOfApplicant>
      <ncom:signature>Luis Berruga</ncom:signature>
      <ncom:signerName>Luis Berruga</ncom:signerName>
      <ncom:title>President</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
