The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
VBI Vaccines Inc. COM 91822J103 6,512 2,691,042 SH   DFND   2,691,042 0 0
Sientra Inc. COM 82621J105 65,211 2,730,765 SH   DFND   2,730,765 0 0
Nanostring Technologies Inc. COM 63009R109 71,962 4,036,025 SH   DFND   3,959,440 0 0
Catabasis Pharmaceuticals Inc. COM 14875P107 1,606 2,008,192 SH   DFND   2,008,192 0 0
Restoration Robotics Inc. COM 76133C103 10,353 3,569,986 SH   DFND   3,569,986 0 0
ESSA Pharma Inc. COM 29668H708 5,006 1,668,560 SH   DFND   1,668,560 0 0
AvroBio Inc. COM 05455M100 153,656 2,962,325 SH   DFND   2,962,325 0 0
Forty Seven Inc COM 34983P104 56,949 3,816,951 SH   DFND   3,816,951 0 0
Entasis Therapeutics Holdings Inc COM 293614103 17,663 1,623,405 SH   DFND   1,623,405 0 0
Gritstone Oncology Inc COM 39868T105 36,560 2,567,445 SH   DFND   2,567,445 0 0