Statements of Stockholders' Equity - USD ($) $ in Thousands	Common Stock	Additional Paid-in Capital	Accumulated Deficit	Accumulated Other Comprehensive Income (Loss)	Total
Beginning Balance at Dec. 31, 2021	$ 7	$ 558,725	$ (494,102)	$ 64,630
Beginning Balance (in shares) at Dec. 31, 2021	6,618,096
Increase (Decrease) in Stockholders' Equity
Stock-based compensation expense		1,155		1,155
Net loss			(16,389)	(16,389)	$ (16,389)
Ending Balance at Mar. 31, 2022	$ 7	559,880	(510,491)	49,396
Ending Balance (in shares) at Mar. 31, 2022	6,618,096
Beginning Balance at Dec. 31, 2022	$ 8	563,362	(547,772)	1	$ 15,599
Beginning Balance (in shares) at Dec. 31, 2022	7,744,692				7,744,692
Beginning Balance (in shares) at Dec. 31, 2022					0
Increase (Decrease) in Stockholders' Equity
Stock-based compensation expense		806			$ 806
Exercise of pre-funded warrants and related reclassification of warrant liability	$ 1	1,568			1,569
Exercise of pre-funded warrants and related reclassification of warrant liability (in shares)	1,230,380
Unrealized loss on marketable securities				$ (1)	(1)
Net loss			(7,819)		(7,819)
Ending Balance at Mar. 31, 2023	$ 9	$ 565,736	$ (555,591)		$ 10,154
Ending Balance (in shares) at Mar. 31, 2023	8,975,072				8,975,072
Ending Balance (in shares) at Mar. 31, 2023					0