Stockholders' Equity (Tables)

9 Months Ended

Sep. 30, 2022

Stockholders' Equity

Summary of net proceeds from the Preferred Stock Transaction

Common Stock Warrant liability	$	1,519
Series A and Series B Preferred Stock		481
Gross Proceeds	$	2,000

Schedule of changes in the fair value of the Company's warrant liability representing a recurring measurement classified within Level 3, wherein fair value is estimated using significant unobservable inputs

	July 29,		September 30,
	2022		2022
Expected term of warrants (in years)	5.0		4.8
Risk-free interest rate	2.7	%	4.1	%
Expected volatility	104.3	%	105.5	%
Dividend yield	—	%	—	%

Summary of roll forward of the Common Stock Warrant liability

Date of issuance, July 29, 2022	$	1,519
Change in fair value		(651)
Balance, September 30, 2022	$	868

Schedule of share-based compensation expense recognized

The estimated grant date fair value of the Company’s share-based awards is amortized on a straight-line basis over the awards’ service periods. Share based compensation expense recognized was as follows (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
Research and development	$	178	$	279	$	672	$	787
Selling, general and administrative		601		690		2,257		2,455
Cost of goods sold		(15)		9		(2)		29
Total stock-based compensation	$	764	$	978	$	2,927	$	3,271

Summary of stock option activity

	Options Outstanding
				Weighted
				Average
		Weighted		Remaining
		Average		Contractual
	Number of	Exercise		Term
	Shares	Price		(in years)
Balance, December 31, 2021	12,449,870	$	2.67	7.11
Granted	999,950		0.46
Exercised	—		—
Forfeited/Cancelled	(4,080,550)		3.72
Balance, September 30, 2022	9,369,270	$	1.97	7.05
Vested or expected to vest at September 30, 2022	9,369,270	$	1.97	7.05
Exercisable at September 30, 2022	5,875,106	$	2.32	6.03

Schedule of weighted-average assumptions:

	September 30,
	2022		2021
Expected term of options (in years)	5.7		6.1
Risk-free interest rate	2.7	%	0.9	%
Expected volatility	98.0	%	97.8	%
Dividend yield	—	%	—	%

Schedule of changes in the status of non-vested RSU

		Weighted
		Average
	Number of	Grant Date
	Awards	Fair Value
Non-vested at December 31, 2021	5,918,496	$	1.08
Granted	—
Vested	(167,953)		0.82
Forfeited	(994,399)		1.22
Non-vested at September 30, 2022	4,756,144	$	1.06

Schedule of shares available to be granted under equity incentive plans

At September 30, 2022, the Company has the following shares available to be granted under its equity incentive plans:

		Inducement
	2013 Plan	Plan
Available at December 31, 2021	4,178,805	252,500
Authorized	6,620,800	—
Granted	(999,950)	—
Forfeited/Cancelled	4,883,886	47,500
Available at September 30, 2022	14,683,541	300,000

Schedule of shares of common stock reserved/available

At September 30, 2022, the Company has reserved the following shares of common stock for issuance:

Stock options outstanding under 2013 Plan	9,169,270
Restricted stock units outstanding under 2013 Plan	4,756,144
Stock options outstanding under Inducement Plan	200,000
Shares reserved for future issuance under Inducement Plan	300,000
Shares reserved for future issuance under 2013 Employee Stock Purchase Plan	225,806
Warrants outstanding	5,275,430
Total shares of common stock reserved for future issuance	19,926,650