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Stockholder's Equity - Shares Reserved for Future Grant and Issuance (Details) - shares
3 Months Ended
Mar. 31, 2020
Mar. 31, 2020
Dec. 31, 2019
Shares Reserved for Future Issuance      
Stock options outstanding (in shares)   7,590,430 7,568,304
Warrants outstanding (in shares)   623,091  
Total shares of common stock reserved for issuance (in shares)   19,730,637  
2013 plan      
Shares Available for Future Grant      
Balance at the beginning of the period (in shares) 4,394,301    
Authorized (in shares) 3,768,550    
Granted (in shares) (480,000)    
Forfeitures/Expirations (in shares) 302,524    
Balance at the end of the period (in shares) 7,985,375    
Shares Reserved for Future Issuance      
Shares available for future grant (in shares) 7,985,375 7,985,375 4,394,301
Inducement Plan      
Shares Available for Future Grant      
Balance at the beginning of the period (in shares) 205,000    
Forfeitures/Expirations (in shares) 23,750    
Balance at the end of the period (in shares) 228,750    
Shares Reserved for Future Issuance      
Shares available for future grant (in shares) 228,750 228,750 205,000
Employee Stock Purchase Plan [Member]      
Shares Reserved for Future Issuance      
Total shares of common stock reserved for issuance (in shares)   225,806  
Employee Stock Option | 2013 plan      
Shares Reserved for Future Issuance      
Stock options outstanding (in shares)   7,319,180  
Employee Stock Option | Inducement Plan      
Shares Reserved for Future Issuance      
Stock options outstanding (in shares)   271,250  
Restricted Stock Units | 2013 plan      
Shares Reserved for Future Issuance      
Total shares of common stock reserved for issuance (in shares)   3,077,185