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Stockholders' Equity - Equity Incentive Plans (Details) - USD ($)
$ in Thousands
3 Months Ended
Dec. 15, 2016
Mar. 31, 2020
Mar. 31, 2019
Equity Incentive Plans      
Stock-based compensation   $ 891 $ 754
Research and Development Expense      
Equity Incentive Plans      
Stock-based compensation   209 232
General and Administrative Expense      
Equity Incentive Plans      
Stock-based compensation   $ 682 $ 522
Maximum      
Equity Incentive Plans      
Term of award   10 years  
Vesting period   4 years  
2008 Plan and 2013 Plan      
Equity Incentive Plans      
Authorized (in shares) 500,000