X0306 4 2017-01-06 0 0001429560 TREVENA INC TRVN 0001591475 Soergel David C/O TREVENA, INC. 1018 WEST 8TH AVENUE, SUITE A KING OF PRUSSIA PA 19406 0 1 0 0 Sr. VP,Clinical Dev. & CMO Employee Stock Option (Right to Buy) 6.61 2017-01-06 4 A 0 55000 0.00 A 2027-01-06 Common Stock 55000 55000 D The option shall vest and become exercisable with respect to one-fourth of the total number of shares subject to the option on each of January 6, 2018, January 6, 2019, January 6, 2020 and January 6, 2021, subject to the reporting person's Continuous Service (as defined in the Trevena, Inc. 2013 Equity Incentive Plan, as amended) as of each such vesting date. /s/John Limongelli, Attorney-in-Fact 2017-01-06