Commitments and Contingencies - Manufacturing Agreements (Details) € in Millions, SFr in Millions, $ in Millions					1 Months Ended					38 Months Ended	49 Months Ended
	Feb. 27, 2018	Jun. 01, 2017	Jun. 28, 2016 USD ($)	Jun. 28, 2016 EUR (€)	Dec. 31, 2020 USD ($)	May 31, 2020 USD ($)	May 31, 2020 CHF (SFr)	Jun. 30, 2016	Jun. 30, 2009	Dec. 03, 2021 USD ($)	Mar. 31, 2022 USD ($)
3M Company | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Additional payments to be made upon achievement of certain sales milestones					$ 30.0
3M And Kindeva | 3M Company | Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Initial term	5 years
Renewal term	3 years								1 year
Termination period	24 months								90 days
Nonrefundable, non-creditable payment										$ 31.8	$ 63.0
Ypsomed Supply Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Services agreement, term		3 years
Services agreement, renewal term		2 years				2 years	2 years	2 years
Services agreement, additional renewal term		2 years						2 years
Service agreement, period required for notice of non-renewal		18 months
Total minimum payments inclusive of milestone payments and one-time capacity fee						$ 2.1	SFr 1.9
Services agreement, termination period								2 years
Lonza Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Services agreement, term			6 years	6 years
Services agreement, renewal term			3 years	3 years
Service agreement, period required for notice of non-renewal			24 years	24 years
Collaborative arrangements, annual minimum batches			$ 3.1	€ 2.9
Collaborative arrangements, aggregate minimum payments			$ 17.2
Fresh Cut Development L L C
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Additional payments to be made upon achievement of certain clinical and regulatory milestones					$ 60.0
Collaborative arrangement, expected milestone payments											$ 2.5