Product Revenue Reserves and Allowances (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Product Revenue Allowance and Reserves
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	$ 19,107	$ 24,602
Provision related to sales in the current year	92,650	75,273
Adjustments related to prior period sales	(3,300)	(1,677)
Credits and payments made	(76,681)	(71,621)
Ending balance	31,776	26,577
Chargebacks, Discounts, and Fees
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	1,891	5,739
Provision related to sales in the current year	14,524	16,123
Adjustments related to prior period sales	(61)	(107)
Credits and payments made	(14,630)	(20,011)
Ending balance	1,724	1,744
Government and other rebates
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	14,644	17,280
Provision related to sales in the current year	77,804	57,120
Adjustments related to prior period sales	(990)	(1,570)
Credits and payments made	(61,862)	(50,717)
Ending balance	29,596	22,113
Returns
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	2,572	1,583
Provision related to sales in the current year	322	2,030
Adjustments related to prior period sales	(2,249)	0
Credits and payments made	(189)	(893)
Ending balance	$ 456	$ 2,720