Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands		3 Months Ended		9 Months Ended
		Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
REVENUES:
Total revenue		$ 56,810	$ 77,826	$ 164,867	$ 175,862
OPERATING EXPENSES:
Cost of sales - product		4,873	3,839	13,192	11,771
Cost of sales - intangible amortization		200	200	599	599
Research and development, net of amounts reimbursable	[1]	34,738	39,450	93,128	123,340
Selling, general and administrative		34,256	33,692	100,496	108,356
(Loss) income from operations		(17,257)	645	(42,548)	(68,204)
OTHER INCOME (EXPENSE):
Other income (expense)		90	(87)	10	(144)
Interest expense		(4,873)	(7,069)	(14,084)	(20,747)
Interest income		7	222	70	1,272
Gain on extinguishment of debt		0	0	1,960	0
NET LOSS		(22,033)	(6,289)	(54,592)	(87,823)
OTHER COMPREHENSIVE LOSS:
Unrealized (gain) loss from available-for-sale debt securities		0	(26)	(21)	79
COMPREHENSIVE LOSS		(22,033)	(6,315)	(54,613)	(87,744)
LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS - BASIC		(22,033)	(6,289)	(54,592)	(87,823)
LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS - DILUTED		$ (22,033)	$ (6,289)	$ (54,592)	$ (87,823)
LOSS PER SHARE:
Basic (in dollars per share)		$ (0.47)	$ (0.14)	$ (1.16)	$ (1.89)
Diluted (in dollars per share)		$ (0.47)	$ (0.14)	$ (1.16)	$ (1.89)
WEIGHTED AVERAGE SHARES:
Basic (in shares)		47,288,212	46,493,126	47,173,337	46,395,124
Diluted (in shares)		47,288,212	46,493,126	47,173,337	46,395,124
Product revenue, net
REVENUES:
Total revenue		$ 56,810	$ 50,412	$ 153,867	$ 148,448
License revenue
REVENUES:
Total revenue		$ 0	$ 27,414	$ 11,000	$ 27,414

[1] Amounts reimbursable for the three and nine months ended September 30, 2021 were $14.6 million and $47.4 million, respectively, and $15.4 million for the three and nine months ended September 30, 2020.