Product Revenue Reserves and Allowances (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020
Product Revenue Allowance and Reserves
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	$ 19,107	$ 24,602
Provision related to sales in the current year	62,386	50,465
Adjustments related to prior period sales	(3,292)	(2,569)
Credits and payments made	(52,725)	(52,874)
Ending balance	25,476	19,624
Chargebacks, Discounts, and Fees
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	1,891	5,739
Provision related to sales in the current year	9,313	12,129
Adjustments related to prior period sales	(54)	(294)
Credits and payments made	(9,677)	(15,390)
Ending balance	1,473	2,184
Government and other rebates
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	14,644	17,280
Provision related to sales in the current year	52,886	34,448
Adjustments related to prior period sales	(989)	(826)
Credits and payments made	(42,859)	(36,805)
Ending balance	23,682	14,097
Returns
Summary of Activity of Product Revenue Allowance and Reserves
Beginning balance	2,572	1,583
Provision related to sales in the current year	187	3,888
Adjustments related to prior period sales	(2,249)	(1,449)
Credits and payments made	(189)	(679)
Ending balance	$ 321	$ 3,343