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Accrued Expenses and Other Current Liabilities (Tables)
12 Months Ended
Dec. 31, 2019
Payables and Accruals [Abstract]  
Schedule of accrued expenses
Accrued expenses as of December 31, 2019 and 2018 consist of the following (in thousands):
 
December 31,
 
2019
 
2018
Commercial costs
$
3,514

 
$
2,884

Product revenue reserves
17,280

 
7,620

Royalty payable
2,797

 
1,735

Research costs
13,049

 
10,403

Payroll and employee benefits
11,551

 
12,230

Interest
3,050

 
3,050

Professional fees
1,439

 
3,465

Restructuring
255

 
613

Other current liabilities
95

 
203

Total accrued expenses and other current liabilities
$
53,030

 
$
42,203