Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
OPERATING EXPENSES:
Cost of sales - intangible amortization	$ 200	$ 200	$ 599	$ 599
Research and development	31,791	26,804	82,230	75,979
Selling, general and administrative	35,617	43,661	116,918	140,266
Other operating expenses	0	0	0	10,801
Loss from operations	(24,813)	(45,219)	(92,904)	(167,714)
OTHER INCOME (EXPENSE):
Other income (expense)	59	17	21	83
Interest expense	(6,298)	(5,793)	(18,500)	(17,041)
Interest income	1,008	1,193	3,105	4,433
NET LOSS	(30,044)	(49,802)	(108,278)	(180,239)
OTHER COMPREHENSIVE LOSS:
Unrealized gain (loss) from available-for-sale debt securities	66	442	776	(534)
COMPREHENSIVE LOSS	(29,978)	(49,360)	(107,502)	(180,773)
LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS - BASIC AND DILUTED (Note 11)	$ (30,044)	$ (49,802)	$ (108,278)	$ (180,239)
LOSS PER SHARE:
Basic and diluted (in dollars per share)	$ (0.65)	$ (1.09)	$ (2.36)	$ (3.98)
WEIGHTED AVERAGE SHARES:
Basic and diluted (in shares)	46,141,217	45,498,909	45,975,691	45,291,176
Product
REVENUES:
Product revenue, net	$ 46,766	$ 27,639	$ 117,652	$ 64,815
OPERATING EXPENSES:
Cost of sales - product	$ 3,971	$ 2,193	$ 10,809	$ 4,884