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Accrued Expenses and Other Current Liabilities (Tables)
9 Months Ended
Sep. 30, 2019
Payables and Accruals [Abstract]  
Schedule of accrued expenses and other current liabilities
Accrued expenses and other current liabilities consisted of the following for the periods set forth below (in thousands):
 
September 30,
2019
 
December 31,
2018
Commercial costs
$
3,179

 
$
2,884

Product revenue reserves
18,561

 
7,620

Royalty payable
2,352

 
1,735

Research and development costs
9,329

 
10,403

Payroll and employee benefits
10,275

 
12,230

Interest
763

 
3,050

Professional fees
4,516

 
3,465

Restructuring costs
12

 
613

Other current liabilities
95

 
203

Total accrued expenses and other current liabilities
$
49,082

 
$
42,203