Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
OPERATING EXPENSES:
Cost of sales - intangible amortization	$ 200	$ 200	$ 399	$ 399
Research and development	27,179	26,324	50,439	49,175
Selling, general and administrative	40,115	48,579	81,301	96,605
Other operating expenses	0	10,801	0	10,801
Loss from operations	(30,260)	(64,878)	(68,091)	(122,495)
OTHER INCOME (EXPENSE):
Other income (expense)	(42)	171	(38)	66
Interest expense	(6,165)	(5,683)	(12,202)	(11,248)
Interest income	993	1,508	2,097	3,240
NET LOSS	(35,474)	(68,882)	(78,234)	(130,437)
OTHER COMPREHENSIVE LOSS:
Unrealized gain (loss) from available-for-sale debt securities	236	192	710	(976)
COMPREHENSIVE LOSS	(35,238)	(68,690)	(77,524)	(131,413)
LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS - BASIC AND DILUTED (Note 11)	$ (35,474)	$ (68,882)	$ (78,234)	$ (130,437)
LOSS PER SHARE:
Basic and diluted (in dollars per share)	$ (0.77)	$ (1.52)	$ (1.70)	$ (2.89)
WEIGHTED AVERAGE SHARES:
Basic and diluted (in shares)	46,109,193	45,430,678	45,891,557	45,185,588
Product
REVENUES:
Product revenue, net	$ 41,042	$ 22,629	$ 70,886	$ 37,176
OPERATING EXPENSES:
Cost of sales - product	$ 3,808	$ 1,603	$ 6,838	$ 2,691