Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
OPERATING EXPENSES:
Cost of sales - intangible amortization	$ 200	$ 200
Research and development	23,259	22,851
Selling, general and administrative	41,186	48,025
Loss from operations	(37,831)	(57,617)
OTHER (EXPENSE) INCOME:
Other income (expense)	4	(104)
Interest expense	(6,037)	(5,566)
Interest income	1,104	1,732
NET LOSS	(42,760)	(61,555)
OTHER COMPREHENSIVE LOSS:
Unrealized gain (loss) from available-for-sale debt securities	474	(1,169)
COMPREHENSIVE LOSS	(42,286)	(62,724)
LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS - BASIC AND DILUTED (Note 11)	$ (42,760)	$ (61,555)
LOSS PER SHARE:
Basic and diluted (in dollars per share)	$ (0.94)	$ (1.37)
WEIGHTED AVERAGE SHARES:
Basic and diluted (in shares)	45,671,502	44,937,776
Product
REVENUES:
Product revenue, net	$ 29,844	$ 14,547
OPERATING EXPENSES:
Cost of sales - product	$ 3,030	$ 1,088