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Accrued Expenses and Other Current Liabilities (Tables)
3 Months Ended
Mar. 31, 2019
Payables and Accruals [Abstract]  
Schedule of accrued expenses and other current liabilities
Accrued expenses and other current liabilities consisted of the following for the periods set forth below (in thousands):
 
March 31,
2019
 
December 31,
2018
Commercial costs
$
3,967

 
$
2,884

Product revenue reserves
13,014

 
7,620

Royalty payable
1,505

 
1,735

Research and development costs
5,931

 
10,403

Payroll and employee benefits
6,456

 
12,230

Interest
763

 
3,050

Professional fees
3,481

 
3,465

Restructuring costs
420

 
613

Other current liabilities
95

 
203

Total accrued expenses and other current liabilities
$
35,632

 
$
42,203