Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2018	Dec. 31, 2017
Current assets:
Cash and cash equivalents	$ 59,321	$ 118,564
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents	59,881	118,619
Restricted cash	560	55
Marketable securities	177,140	134,714
Accounts receivable, net	16,758	4,441
Inventory	6,210	4,366
Prepaid expenses	13,842	5,175
Other current assets	1,202	2,191
Total current assets	275,033	269,506
Investments	0	176,978
Property and equipment, net	4,003	6,195
Intangible assets	7,382	8,180
Other assets	544	799
Total assets	286,962	461,658
Current liabilities:
Accounts payable	4,226	3,915
Accrued expenses and other current liabilities	42,203	49,512
Total current liabilities	46,429	53,427
Notes payable	95	189
Other non-current liabilities	179,806	166,006
Total liabilities	226,330	219,622
Commitments and contingencies
Stockholders’ equity:
Common stock, $.0001 par value; 200,000,000 shares authorized, 45,563,693 shares and 44,616,586 shares issued and outstanding at December 31, 2018 and 2017, respectively	5	4
Additional paid-in-capital	1,165,003	1,124,630
Accumulated other comprehensive income (loss)	(755)	(314)
Accumulated deficit	(1,103,621)	(882,284)
Total stockholders’ equity	60,632	242,036
Total liabilities and stockholders’ equity	$ 286,962	$ 461,658