Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017
OPERATING EXPENSES:
Cost of sales - intangible amortization	$ 200	$ 0	$ 399	$ 0
Research and development	26,324	19,652	49,175	39,179
Selling, general and administrative	48,579	50,121	96,605	88,220
Other operating expenses	10,801	0	10,801	0
Loss from operations	(64,878)	(68,898)	(122,495)	(126,524)
OTHER (EXPENSE) INCOME:
Other income (expense)	171	(97)	66	(17)
Interest expense	(5,683)	0	(11,248)	0
Interest income	1,508	557	3,240	1,164
NET LOSS	(68,882)	(68,438)	(130,437)	(125,377)
OTHER COMPREHENSIVE LOSS:
Unrealized gain (loss) from available-for-sale debt securities	192	(32)	(976)	(69)
COMPREHENSIVE LOSS	(68,690)	(68,470)	(131,413)	(125,446)
LOSS ATTRIBUTABLE TO COMMON STOCKHOLDERS - BASIC AND DILUTED	$ (68,882)	$ (68,438)	$ (130,437)	$ (125,377)
LOSS PER SHARE:
Basic and diluted (in dollars per share)	$ (1.52)	$ (1.58)	$ (2.89)	$ (2.90)
WEIGHTED AVERAGE SHARES:
Basic and diluted (in shares)	45,430,678	43,410,053	45,185,588	43,300,243
Product
REVENUES:
Product revenue, net	$ 22,629	$ 980	$ 37,176	$ 980
OPERATING EXPENSES:
Cost of sales - product	$ 1,603	$ 105	$ 2,691	$ 105