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Product Revenue Reserves and Allowances (Tables)
 6 Months Ended
Jun. 30, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of product revenue allowance and reserve categories
The following table summarizes activity in each of the product revenue allowance and reserve categories for the six months ended June 30, 2018 and 2017 (in thousands):
 
Chargebacks, Discounts, and Fees
 
Government and other rebates
 
Returns
 
Total
Beginning balance at December 31, 2017
$
1,986

 
$
1,231

 
$
421

 
$
3,638

Provision related to sales in the current year
8,769

 
6,961

 
517

 
16,247

Adjustments related to prior period sales
(148
)
 
41

 
(110
)
 
(217
)
Credits and payments made
(5
)
 
(1,252
)
 
(295
)
 
(1,552
)
Ending balance at June 30, 2018
$
10,602

 
$
6,981

 
$
533

 
$
18,116

 
 
 
 
 
 
 
 
Beginning balance at December 31, 2016
$
—

 
$
—

 
$
—

 
$
—

Provision related to sales in the current year
271

 
86

 
75

 
432

Adjustments related to prior period sales
—

 
—

 
—

 
—

Credits and payments made
—

 
—

 
—

 
—

Ending balance at June 30, 2017
$
271

 
$
86

 
$
75

 
$
432