Accrued Expenses and Other Current Liabilities (Details) - USD ($) $ in Thousands	Jun. 30, 2017	Dec. 31, 2016
Payables and Accruals [Abstract]
Commercial costs	$ 7,618	$ 4,038
Research costs - Nordic	0	1,228
Research costs - other	5,688	8,404
Payroll and employee benefits	9,888	9,338
Professional fees	4,063	3,494
Other current liabilities	121	95
Total accrued expenses and other current liabilities	$ 27,378	$ 26,597