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License Agreements (Details)
$ in Thousands, € in Millions
3 Months Ended 7 Months Ended 136 Months Ended
Mar. 09, 2015
USD ($)
Mar. 31, 2017
USD ($)
Mar. 31, 2017
EUR (€)
Dec. 31, 2006
USD ($)
Dec. 31, 2016
USD ($)
Apr. 30, 2017
USD ($)
Apr. 30, 2017
EUR (€)
Eisai | License Agreement              
License Agreements              
Initial license fee paid $ 400     $ 500      
Eisai | License Agreement | Maximum              
License Agreements              
Payments to be made upon achievement of certain clinical and regulatory milestones   $ 22,300          
Clinical Trial Services Agreement | Ipsen              
License Agreements              
Nonrefundable, non-creditable payment         $ 4,300    
Royalty rate (as a percent)   5.00% 5.00%        
Clinical Trial Services Agreement | Ipsen | Minimum              
License Agreements              
Period after the date of the first commercial sale of the product for license expiration   10 years 10 years        
Clinical Trial Services Agreement | Ipsen | Maximum              
License Agreements              
Additional payments to be made upon achievement of certain development and commercialization milestones   $ 33,600 € 32.0        
Clinical Trial Services Agreement | Ipsen | Sublicense Agreement              
License Agreements              
Period after the date of the first commercial sale of the product for license expiration   10 years 10 years        
Subsequent Event | Clinical Trial Services Agreement | Ipsen              
License Agreements              
Milestone payments due           $ 8,700 € 8.0