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Net Loss Per Share (Details 2) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Convertible preferred stock      
Net Loss Per Share      
Potentially dilutive securities, prior to the use of the treasury stock method, excluded from the computation of diluted weighted-average shares outstanding, as they would be anti-dilutive (in shares) 0 0 3,857,664
Options to purchase common stock      
Net Loss Per Share      
Potentially dilutive securities, prior to the use of the treasury stock method, excluded from the computation of diluted weighted-average shares outstanding, as they would be anti-dilutive (in shares) 5,815,168 3,903,051 2,466,492
Warrants      
Net Loss Per Share      
Potentially dilutive securities, prior to the use of the treasury stock method, excluded from the computation of diluted weighted-average shares outstanding, as they would be anti-dilutive (in shares) 630,444 822,726 1,271,520
Restricted Stock Units (RSUs)      
Net Loss Per Share      
Potentially dilutive securities, prior to the use of the treasury stock method, excluded from the computation of diluted weighted-average shares outstanding, as they would be anti-dilutive (in shares) 42,363 0 0