Net Loss Per Share (Tables)

12 Months Ended

Dec. 31, 2016

Schedule of basic and diluted net loss per share

Basic and diluted net loss per share is calculated as follows (in thousands, except share and per share amounts):



	Year Ended December 31,
	2016			2015			2014
Numerator:
Net loss	$	(182,804	)	$	(101,526	)	$	(62,479	)
Accretion of preferred stock	—			—			(9,000		)
Loss attributable to common stockholders—basic	(182,804		)	(101,526		)	(71,479		)
Effect of dilutive convertible preferred stock	—			—			—
Loss attributable to common stockholders—diluted	$	(182,804	)	$	(101,526	)	$	(71,479	)
Denominator:
Weighted-average number of common shares used in loss per share— basic and diluted	43,067,952			39,643,099			17,699,487
Loss per share—basic and diluted	$	(4.24	)	$	(2.56	)	$	(4.04	)

Schedule of potentially dilutive securities excluded from the computation of diluted weighted-average shares outstanding

The following potentially dilutive securities, prior to the use of the treasury stock method, have been excluded from the computation of diluted weighted-average shares outstanding, as they would be anti-dilutive. For the years ended December 31, 2016, 2015, and 2014 all of the Company's classes of convertible preferred stock, options to purchase common stock, warrants and performance units outstanding were assumed to be anti-dilutive as earnings attributable to common stockholders was in a loss position.



	Year Ended December 31
	2016	2015	2014
Convertible preferred stock	—	—	3,857,664
Options to purchase common stock	5,815,168	3,903,051	2,466,492
Warrants	630,444	822,726	1,271,520
Restricted Stock Units	42,363	—	—