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Stock-Based Compensation (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 9 Months Ended
Apr. 30, 2016
Sep. 30, 2016
Employee stock option    
Summary of stock option activity - Shares    
Options outstanding at December 31, 2015 (in shares)   4,408,000
Granted (in shares)   2,095,000
Exercised (in shares)   (126,000)
Cancelled (in shares)   (102,000)
Expired (in shares)   (1,000)
Options outstanding at September 30, 2016 (in shares)   6,274,000
Options exercisable at September 30, 2016 (in shares)   2,469,000
Options vested or expected to vest at September 30, 2016 (in shares)   6,153,000
Summary of stock option activity - Weighted-Average Exercise Price (in dollars per share)    
Options outstanding at the beginning of the period (in dollars per share)   $ 28.75
Granted (in dollars per share)   36.10
Exercised (in dollars per share)   19.36
Cancelled (in dollars per share)   42.12
Expired (in dollars per share)   79.90
Options outstanding at the end of the period (in dollars per share)   31.17
Options exercisable at the end of the period (in dollars per share)   19.77
Options vested and expected to vest at the end of the period (in dollars per share)   $ 30.98
Weighted-Average Contractual Life (In Years)    
Options outstanding at the end of the period   8 years 58 days
Options exercisable at the end of the period   6 years 314 days
Options vested and expected to vest at the end of the period   8 years 50 days
Aggregate Intrinsic Value    
Options outstanding at the end of the period (in dollars)   $ 156,384
Options exercisable at the end of the period (in dollars)   87,873
Options vested and expected to vest at the end of the period (in dollars)   $ 154,436
Restricted stock units (RSUs)    
Stock-based Compensation    
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period 4 years  
Restricted Stock Units Awarded (in shares) 58,500  
Summary of restricted stock units activity    
RSUs Outstanding at December 31, 2015 (in shares)   0
Granted (in shares)   59,000
Vested (in shares)   0
Forfeited (in shares)   (2,000)
RSUs Outstanding at September 30, 2016 (in shares)   57,000
Summary of stock option activity - Weighted-Average Grant Date Fair Value (in dollars per share)    
RSUs outstanding at the beginning of the period (in dollars per share)   $ 33.03
Granted (in dollars per share)   33.03
Exercised (in dollars per share)   0.00
Forfeited (in dollars per share)   33.03
RSUs outstanding at the end of the period (in dollars per share)   $ 0.00