Selected Quarterly Financial Data - Unaudited (Tables)

12 Months Ended

Dec. 31, 2015

Selected quarterly financial data for the years ended December 31, 2015 and 2014 is as follows (in thousands, except for share and per share data):

	Three Months Ended
	March 31,			June 30,			September 30,			December 31,
2015:
Net loss	$	(17,057	)		(22,965	)		(28,264	)	$	(33,240	)
Net loss applicable to common stock		(17,057	)		(22,965	)		(28,264	)		(33,240	)
Net loss per share—basic and diluted		(0.47	)		(0.61	)		(0.68	)		(0.77	)
Weighted-average common shares outstanding—basic and diluted		36,268,975			37,895,651			41,331,612			42,924,137
2014:
Net loss	$	(14,488	)	$	(12,609	)	$	(17,420	)	$	(17,962	)
Net loss applicable to common stock		(19,457	)		(16,640	)		(17,420	)		(17,962	)
Net loss per share—basic and diluted		(50.45	)		(2.22	)		(0.59	)		(0.55	)
Weighted-average common shares outstanding—basic and diluted		385,664			7,500,148			29,746,426			32,678,459